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Plc21C - Phospholipase C at 21C

Predicted to enable phosphatidylinositol phospholipase C activity. Involved in several processes, including entrainment of circadian clock by photoperiod; flight behavior; and regulation of neuromuscular synaptic transmission. Is expressed in central nervous system; embryonic/larval digestive system; head; oocyte; and ring gland. Used to study obesity. Human ortholog(s) of this gene implicated in Alzheimer's disease; developmental and epileptic encephalopathy 12; myelodysplastic syndrome; and spondylometaphyseal dysplasia with corneal dystrophy. Orthologous to several human genes including PLCB1 (phospholipase C beta 1) and PLCB3 (phospholipase C beta 3). [provided by Alliance of Genome Resources, Apr 2022]

NCBI Orthologs

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Species Gene Architecture aa