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ppme1 protein phosphatase methylesterase 1 [ Danio rerio (zebrafish) ]

Gene ID: 335124, updated on 27-Mar-2024

Summary

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Official Symbol
ppme1provided by ZNC
Official Full Name
protein phosphatase methylesterase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7064
See related
Ensembl:ENSDARG00000009771 AllianceGenome:ZFIN:ZDB-GENE-030131-7064
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fk72d03; zgc:56239; wu:fk72d03
Summary
Predicted to enable protein methylesterase activity. Predicted to be involved in protein demethylation. Orthologous to human PPME1 (protein phosphatase methylesterase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See ppme1 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (25380675..25395155, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (25344070..25358550, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene odorant receptor, family 92, subfamily A, member 3 Neighboring gene odorant receptor, family 92, subfamily A, member 2 Neighboring gene odorant receptor, family 92, subfamily A, member 7 Neighboring gene spermine synthase Neighboring gene uncharacterized LOC101886303 Neighboring gene connector enhancer of kinase suppressor of Ras 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Cd248a and Cd248b in zebrafish participate in innate immune responses. Li X, et al. Front Immunol, 2022. PMID 36119065, Free PMC Article
  2. Genomic organization and evolution of olfactory receptors and trace amine-associated receptors in channel catfish, Ictalurus punctatus. Gao S, et al. Biochim Biophys Acta Gen Subj, 2017 Mar. PMID 27773705
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein methylesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein methylesterase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein demethylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein phosphatase methylesterase 1
NP_956231.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199937.1 → NP_956231.1  protein phosphatase methylesterase 1

    See identical proteins and their annotated locations for NP_956231.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046016
    UniProtKB/TrEMBL
    Q6IQF9, Q7ZV37
    Related
    ENSDARP00000018567.7, ENSDART00000016219.9
    Conserved Domains (3) summary
    COG0596
    Location:69 → 367
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    pfam12695
    Location:74 → 165
    Abhydrolase_5; Alpha/beta hydrolase family
    cl17036
    Location:265 → 303
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    25380675..25395155 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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