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sult1st3 sulfotransferase family 1, cytosolic sulfotransferase 3 [ Danio rerio (zebrafish) ]

Gene ID: 368270, updated on 27-Mar-2024

Summary

Official Symbol
sult1st3provided by ZNC
Official Full Name
sulfotransferase family 1, cytosolic sulfotransferase 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030804-28
See related
Ensembl:ENSDARG00000018361 AllianceGenome:ZFIN:ZDB-GENE-030804-28
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92322; wu:fj78b11
Summary
Enables sulfotransferase activity. Involved in xenobiotic metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; gastrointestinal system cancer (multiple); lung cancer (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to human SULT1A1 (sulfotransferase family 1A member 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See sult1st3 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (46559332..46581443, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (46551453..46573569, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene sulfotransferase family 1, cytosolic sulfotransferase 2 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 186 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 187 Neighboring gene taste receptor, type 1, member 2, tandem duplicate 1 Neighboring gene taste receptor, type 1, member 2, tandem duplicate 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables aryl sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sulfotransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within catecholamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within steroid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in sulfation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cytosolic sulfotransferase 3
Names
SULT1 ST3
NP_899191.2
XP_005172522.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183348.2NP_899191.2  cytosolic sulfotransferase 3

    See identical proteins and their annotated locations for NP_899191.2

    Status: PROVISIONAL

    Source sequence(s)
    BC076007
    UniProtKB/Swiss-Prot
    Q7T2V2
    UniProtKB/TrEMBL
    A0A8M1P8Q6, E7F5H9, Q6DHG7
    Related
    ENSDARP00000030002.3, ENSDART00000030470.4
    Conserved Domains (1) summary
    pfam00685
    Location:43294
    Sulfotransfer_1; Sulfotransferase domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    46559332..46581443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005172465.2XP_005172522.1  cytosolic sulfotransferase 3 isoform X1

    See identical proteins and their annotated locations for XP_005172522.1

    UniProtKB/Swiss-Prot
    Q7T2V2
    UniProtKB/TrEMBL
    A0A8M1P8Q6, E7F5H9, Q6DHG7
    Related
    ENSDARP00000006665.8, ENSDART00000014240.10
    Conserved Domains (1) summary
    pfam00685
    Location:43294
    Sulfotransfer_1; Sulfotransferase domain