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Arms Ankyrin repeat-rich membrane spanning [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37433, updated on 10-May-2024

Summary

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Official Symbol
Armsprovided by FlyBase
Official Full Name
Ankyrin repeat-rich membrane spanningprovided by FlyBase
Primary source
FLYBASE:FBgn0261554
Locus tag
Dmel_CG42672
See related
AllianceGenome:FB:FBgn0261554
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
ARMS; CG10074; CG15665; CG30386; CG30387; CG42672; dARMS; Dmel\CG42672; KIDINS220
Old locus tag
Dmel_CG30386; Dmel_CG30387
Summary
Is expressed in adult head. Orthologous to human KIDINS220 (kinase D interacting substrate 220). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Arms in Genome Data Viewer
Location:
57D8-57D11; 2-94 cM
Exon count:
18
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21295652..21310411)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17183157..17197916)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene SAGA-associated factor 29kDa Neighboring gene Ribosomal protein L29 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44724 Neighboring gene antisense RNA:CR45149 Neighboring gene Panoramix Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ARMS-NF-κB signaling regulates intracellular ROS to induce autophagy-associated cell death upon oxidative stress. Liao YH, et al. iScience, 2023 Feb 17. PMID 36798436, Free PMC Article
  2. Mutations disrupting neuritogenesis genes confer risk for cerebral palsy. Jin SC, et al. Nat Genet, 2020 Oct. PMID 32989326, Free PMC Article
  3. In Depth Exploration of the Alternative Proteome of Drosophila melanogaster. Fabre B, et al. Front Cell Dev Biol, 2022. PMID 35721519, Free PMC Article
  4. Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster. Harbison ST, et al. Behav Genet, 2019 Jan. PMID 30341464, Free PMC Article
  5. A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Friedman A, et al. Nature, 2006 Nov 9. PMID 17086199

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables PDZ domain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of negative regulation of reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
ankyrin repeat-rich membrane spanning
Names
Arms-PD
Arms-PF
Arms-PG
Arms-PI
Arms-PJ
Arms-PK
Arms-PL
Arms-PM
Arms-PO
Arms-PP
Arms-PQ
Arms-PR
Arms-PS
Arms-PT
Arms-PU
Arms-PV
CG42672-PD
CG42672-PF
CG42672-PG
CG42672-PI
CG42672-PJ
CG42672-PK
CG42672-PL
CG42672-PM
CG42672-PO
CG42672-PP
CG42672-PQ
CG42672-PR
CG42672-PS
CG42672-PT
CG42672-PU
CG42672-PV

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    21295652..21310411
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166441.4 → NP_726059.5  ankyrin repeat-rich membrane spanning, isoform P [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726059.5

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2I0
    Conserved Domains (7) summary
    cd09487
    Location:1357 → 1392
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:231 → 355
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:605 → 1136
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:240 → 332
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:401 → 454
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:518 → 575
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:235 → 266
    ANK; ANK repeat [structural motif]

  2. NM_001299745.1 → NP_001286674.1  ankyrin repeat-rich membrane spanning, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286674.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LH32
    Conserved Domains (7) summary
    cd09487
    Location:1193 → 1228
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:67 → 191
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:441 → 972
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:76 → 168
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:237 → 290
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:354 → 411
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:71 → 102
    ANK; ANK repeat [structural motif]

  3. NM_001169762.2 → NP_001163233.1  ankyrin repeat-rich membrane spanning, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163233.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JGQ4
    Conserved Domains (7) summary
    cd09487
    Location:1193 → 1228
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:67 → 191
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:441 → 972
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:76 → 168
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:237 → 290
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:354 → 411
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:71 → 102
    ANK; ANK repeat [structural motif]

  4. NM_137730.4 → NP_611574.5  ankyrin repeat-rich membrane spanning, isoform O [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611574.5

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KVP6
    Conserved Domains (7) summary
    cd09487
    Location:1357 → 1392
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:231 → 355
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:605 → 1136
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:240 → 332
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:401 → 454
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:518 → 575
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:235 → 266
    ANK; ANK repeat [structural motif]

  5. NM_001144252.3 → NP_001137724.1  ankyrin repeat-rich membrane spanning, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137724.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7YZM7
    Conserved Domains (7) summary
    cd09487
    Location:1193 → 1228
    SAM_superfamily; SAM (Sterile alpha motif )
    COG0666
    Location:320 → 441
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd00204
    Location:67 → 191
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:441 → 972
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:76 → 168
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:237 → 290
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:71 → 102
    ANK; ANK repeat [structural motif]

  6. NM_001382092.1 → NP_001369103.1  ankyrin repeat-rich membrane spanning, isoform S [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3Q9J1
    Conserved Domains (6) summary
    PTZ00322
    Location:24 → 112
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    cd09487
    Location:1208 → 1243
    SAM_superfamily; SAM (Sterile alpha motif )
    PHA03095
    Location:70 → 345
    PHA03095; ankyrin-like protein; Provisional
    pfam07693
    Location:456 → 987
    KAP_NTPase; KAP family P-loop domain
    sd00045
    Location:86 → 117
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:325 → 404
    Ank_2; Ankyrin repeats (3 copies)

  7. NM_001382093.1 → NP_001369104.1  ankyrin repeat-rich membrane spanning, isoform T [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3Q8I0
    Conserved Domains (5) summary
    PHA02874
    Location:89 → 456
    PHA02874; ankyrin repeat protein; Provisional
    cd09487
    Location:1208 → 1243
    SAM_superfamily; SAM (Sterile alpha motif )
    COG0666
    Location:2 → 143
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    pfam07693
    Location:456 → 987
    KAP_NTPase; KAP family P-loop domain
    sd00045
    Location:86 → 117
    ANK; ANK repeat [structural motif]

  8. NM_001382090.1 → NP_001369101.1  ankyrin repeat-rich membrane spanning, isoform Q [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3Q8E0
    Conserved Domains (6) summary
    PTZ00322
    Location:49 → 137
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    cd09487
    Location:1233 → 1268
    SAM_superfamily; SAM (Sterile alpha motif )
    PHA03095
    Location:95 → 370
    PHA03095; ankyrin-like protein; Provisional
    pfam07693
    Location:481 → 1012
    KAP_NTPase; KAP family P-loop domain
    sd00045
    Location:111 → 142
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:350 → 429
    Ank_2; Ankyrin repeats (3 copies)

  9. NM_001382091.1 → NP_001369102.1  ankyrin repeat-rich membrane spanning, isoform R [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3QHD0
    Conserved Domains (5) summary
    PHA02874
    Location:114 → 481
    PHA02874; ankyrin repeat protein; Provisional
    cd09487
    Location:1233 → 1268
    SAM_superfamily; SAM (Sterile alpha motif )
    COG0666
    Location:29 → 168
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    pfam07693
    Location:481 → 1012
    KAP_NTPase; KAP family P-loop domain
    sd00045
    Location:111 → 142
    ANK; ANK repeat [structural motif]

  10. NM_166442.3 → NP_726060.3  ankyrin repeat-rich membrane spanning, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726060.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KVP5
    Conserved Domains (7) summary
    cd09487
    Location:1267 → 1302
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:141 → 265
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:515 → 1046
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:150 → 242
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:311 → 364
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:428 → 485
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:145 → 176
    ANK; ANK repeat [structural motif]

  11. NM_001144253.2 → NP_001137725.1  ankyrin repeat-rich membrane spanning, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137725.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7YZM5
    Conserved Domains (7) summary
    cd09487
    Location:1267 → 1302
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:141 → 265
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:515 → 1046
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:150 → 242
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:311 → 364
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:428 → 485
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:145 → 176
    ANK; ANK repeat [structural motif]

  12. NM_001144251.3 → NP_001137723.2  ankyrin repeat-rich membrane spanning, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137723.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7YZM3
    Conserved Domains (7) summary
    cd09487
    Location:1215 → 1250
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:89 → 213
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:463 → 994
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:98 → 190
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:259 → 312
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:376 → 433
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:93 → 124
    ANK; ANK repeat [structural motif]

  13. NM_001144254.3 → NP_001137726.1  ankyrin repeat-rich membrane spanning, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137726.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7YZM6
    Conserved Domains (7) summary
    cd09487
    Location:1215 → 1250
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:89 → 213
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:463 → 994
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:98 → 190
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:259 → 312
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:376 → 433
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:93 → 124
    ANK; ANK repeat [structural motif]

  14. NM_001382094.1 → NP_001369105.1  ankyrin repeat-rich membrane spanning, isoform U [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3QHJ1
    Conserved Domains (6) summary
    cd09487
    Location:1233 → 1268
    SAM_superfamily; SAM (Sterile alpha motif )
    PHA03095
    Location:95 → 370
    PHA03095; ankyrin-like protein; Provisional
    COG0666
    Location:16 → 168
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    pfam07693
    Location:481 → 1012
    KAP_NTPase; KAP family P-loop domain
    sd00045
    Location:111 → 142
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:350 → 429
    Ank_2; Ankyrin repeats (3 copies)

  15. NM_001144250.2 → NP_001137722.2  ankyrin repeat-rich membrane spanning, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137722.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7YZM4
    Conserved Domains (7) summary
    cd09487
    Location:1233 → 1268
    SAM_superfamily; SAM (Sterile alpha motif )
    cd00204
    Location:107 → 231
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam07693
    Location:481 → 1012
    KAP_NTPase; KAP family P-loop domain
    pfam12796
    Location:116 → 208
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:277 → 330
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:394 → 451
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:111 → 142
    ANK; ANK repeat [structural motif]

  16. NM_001382095.1 → NP_001369106.1  ankyrin repeat-rich membrane spanning, isoform V [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3Q832
    Conserved Domains (5) summary
    PHA02874
    Location:114 → 481
    PHA02874; ankyrin repeat protein; Provisional
    cd09487
    Location:1233 → 1268
    SAM_superfamily; SAM (Sterile alpha motif )
    COG0666
    Location:16 → 168
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    pfam07693
    Location:481 → 1012
    KAP_NTPase; KAP family P-loop domain
    sd00045
    Location:111 → 142
    ANK; ANK repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LH32 A0A0B4LH32
A0A6M3Q832 A0A6M3Q832
A0A6M3Q8E0 A0A6M3Q8E0
A0A6M3Q8I0 A0A6M3Q8I0
A0A6M3Q9J1 A0A6M3Q9J1
A0A6M3QHD0 A0A6M3QHD0
A0A6M3QHJ1 A0A6M3QHJ1
B7YZM3 B7YZM3
B7YZM4 B7YZM4
B7YZM5 B7YZM5
B7YZM6 B7YZM6
B7YZM7 B7YZM7
E1JGQ4 E1JGQ4
Q7KVP5 Q7KVP5
Q7KVP6 Q7KVP6
Q7YU92 Q7YU92
Q9W2I0 Q9W2I0

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