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zgc:77439 zgc:77439 [ Danio rerio (zebrafish) ]

Gene ID: 378987, updated on 27-Mar-2024

Summary

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Official Symbol
zgc:77439provided by ZNC
Official Full Name
zgc:77439provided by ZNC
Primary source
ZFIN:ZDB-GENE-031010-24
See related
Ensembl:ENSDARG00000039211 AllianceGenome:ZFIN:ZDB-GENE-031010-24
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fl33b06; sb:cb897; wu:fb60c01; wu:fb61f06; wu:fj09c12; wu:fl33b06
Summary
Predicted to enable N,N-dimethylaniline monooxygenase activity; NADP binding activity; and flavin adenine dinucleotide binding activity. Acts upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in endoplasmic reticulum. Is expressed in yolk syncytial layer. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See zgc:77439 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (26299854..26308158, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (26028661..26036965, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene transfer RNA serine (anticodon UGA) Neighboring gene zonadhesin, like Neighboring gene trafficking protein particle complex subunit 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology. Lam SH, et al. PLoS Genet, 2008 Jul 11. PMID 18618001, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables N,N-dimethylaniline monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to xenobiotic stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC378987

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001197289.1 → NP_001184218.1  uncharacterized protein LOC378987

    See identical proteins and their annotated locations for NP_001184218.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    CR853281
    UniProtKB/TrEMBL
    Q6NZ32, Q6TLD4
    Related
    ENSDARP00000139015.1, ENSDART00000164627.2
    Conserved Domains (2) summary
    PLN02172
    Location:4 → 400
    PLN02172; flavin-containing monooxygenase FMO GS-OX
    cl21454
    Location:193 → 230
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. NM_212801.2 → NP_997966.1  uncharacterized protein LOC378987

    See identical proteins and their annotated locations for NP_997966.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    CR853281
    UniProtKB/TrEMBL
    Q6NZ32, Q6TLD4
    Related
    ENSDARP00000057287.3, ENSDART00000057288.5
    Conserved Domains (2) summary
    PLN02172
    Location:4 → 400
    PLN02172; flavin-containing monooxygenase FMO GS-OX
    cl21454
    Location:193 → 230
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    26299854..26308158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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