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ppt2a.2 palmitoyl-protein thioesterase 2a, tandem duplicate 2 [ Danio rerio (zebrafish) ]

Gene ID: 393135, updated on 27-Mar-2024

Summary

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Official Symbol
ppt2a.2provided by ZNC
Official Full Name
palmitoyl-protein thioesterase 2a, tandem duplicate 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-762
See related
Ensembl:ENSDARG00000010782 Ensembl:ENSDARG00000068846 AllianceGenome:ZFIN:ZDB-GENE-040426-762
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:55621; si:ch73-95l15.4
Summary
Predicted to enable palmitoyl-(protein) hydrolase activity. Orthologous to human PPT2 (palmitoyl-protein thioesterase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See ppt2a.2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (34934005..34960914)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (35076036..35102945)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 183 Neighboring gene DEAH (Asp-Glu-Ala-His) box polypeptide 16 Neighboring gene palmitoyl-protein thioesterase 2a, tandem duplicate 1 Neighboring gene si:ch73-95l15.5 Neighboring gene tektin like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish model of human Zellweger syndrome reveals organ-specific accumulation of distinct fatty acid species and widespread gene expression changes. Takashima S, et al. Mol Genet Metab, 2021 Jul. PMID 34016526
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC55621

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables palmitoyl hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Lysosomal thioesterase PPT2-A-like; uncharacterized protein LOC393135

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200166.2 → NP_956460.2  Lysosomal thioesterase PPT2-A-like precursor

    See identical proteins and their annotated locations for NP_956460.2

    Status: VALIDATED

    Source sequence(s)
    CO247943, EH545472, EH566605
    UniProtKB/TrEMBL
    A0A8M1PE53, X1WG38
    Related
    ENSDARP00000129193.1, ENSDART00000156515.2
    Conserved Domains (1) summary
    cl21494
    Location:27 → 269
    Abhydrolase; alpha/beta hydrolases

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    34934005..34960914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017359222.2 → XP_017214711.1  uncharacterized protein LOC393135 isoform X2

    UniProtKB/TrEMBL
    A0A8M6Z4C7

  2. XM_017359223.2 → XP_017214712.1  uncharacterized protein LOC393135 isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z9Z8

  3. XM_001923225.5 → XP_001923260.2  uncharacterized protein LOC393135 isoform X1

    UniProtKB/TrEMBL
    A0A8M1QHV2
    Related
    ENSDARP00000128868.1, ENSDART00000155368.3
    Conserved Domains (1) summary
    cl21494
    Location:56 → 292
    Abhydrolase; alpha/beta hydrolases

  4. XM_005157754.4 → XP_005157811.1  uncharacterized protein LOC393135 isoform X4

    UniProtKB/TrEMBL
    A0A8M2B445
    Conserved Domains (1) summary
    cl21494
    Location:27 → 233
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein Strain
Heading Accession and Version

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