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pfdn6 prefoldin subunit 6 [ Danio rerio (zebrafish) ]

Gene ID: 393485, updated on 27-Mar-2024

Summary

Official Symbol
pfdn6provided by ZNC
Official Full Name
prefoldin subunit 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1589
See related
Ensembl:ENSDARG00000037108 AllianceGenome:ZFIN:ZDB-GENE-040426-1589
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:66282
Summary
Predicted to enable chaperone binding activity. Predicted to be involved in chaperone-mediated protein complex assembly and protein folding. Predicted to be part of prefoldin complex. Predicted to be active in cytoplasm. Orthologous to human PFDN6 (prefoldin subunit 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See pfdn6 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (30551321..30557021, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (30211007..30216707, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene hairy-related 11 Neighboring gene hairy-related 5 Neighboring gene mitochondrial ribosomal protein L11 Neighboring gene transmembrane protein 265 Neighboring gene uncharacterized LOC108192168 Neighboring gene neuronal PAS domain protein 4a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC66282

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein-folding chaperone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chaperone-mediated protein complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein folding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of prefoldin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of prefoldin complex IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200513.1NP_956807.1  prefoldin subunit 6

    See identical proteins and their annotated locations for NP_956807.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055580
    UniProtKB/TrEMBL
    B2GQZ7, F6NH43, Q7SX94
    Related
    ENSDARP00000053935.5, ENSDART00000053936.7
    Conserved Domains (1) summary
    cd00632
    Location:9113
    Prefoldin_beta; Prefoldin beta; Prefoldin is a hexameric molecular chaperone complex, composed of two evolutionarily related subunits (alpha and beta), which are found in both eukaryotes and archaea. Prefoldin binds and stabilizes newly synthesized polypeptides ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    30551321..30557021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)