rheb Ras homolog, mTORC1 binding [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rhebprovided by ZNC
Official Full Name: Ras homolog, mTORC1 bindingprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1690
See related: AllianceGenome:ZFIN:ZDB-GENE-040426-1690
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73144
Summary: Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in small GTPase mediated signal transduction. Predicted to act upstream of or within positive regulation of TOR signaling and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human RHEB (Ras homolog, mTORC1 binding). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (41316713..41334617, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (41453394..41456718, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: GTP-binding protein Rheb

Names: Ras homolog enriched in brain

NP_957023.1

EC 3.6.5.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200729.1 → NP_957023.1 GTP-binding protein Rheb

See identical proteins and their annotated locations for NP_957023.1

Status: PROVISIONAL

Source sequence(s)

BC059505

UniProtKB/TrEMBL

Q6PC18

Conserved Domains (1) summary

cd04137
Location:6 → 184

RheB; Ras Homolog Enriched in Brain (RheB) is a small GTPase