rpe65a - retinoid isomerohydrolase RPE65 a
Predicted to enable all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity and retinol isomerase activity. Predicted to be involved in retinoid metabolic process and zeaxanthin biosynthetic process. Predicted to act upstream of or within visual perception. Predicted to be located in endoplasmic reticulum membrane. Is expressed in head and visual system. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 2; retinitis pigmentosa; retinitis pigmentosa 20; and retinitis pigmentosa 87. Orthologous to human RPE65 (retinoid isomerohydrolase RPE65). [provided by Alliance of Genome Resources, Apr 2022]
NCBI Orthologs
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Protein alignment
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