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ssx2ipa synovial sarcoma, X breakpoint 2 interacting protein a [ Danio rerio (zebrafish) ]

Gene ID: 393808, updated on 25-Apr-2024

Summary

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Official Symbol
ssx2ipaprovided by ZNC
Official Full Name
synovial sarcoma, X breakpoint 2 interacting protein aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1756
See related
Ensembl:ENSDARG00000039521 AllianceGenome:ZFIN:ZDB-GENE-040426-1756
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ssx2ip; zgc:73314
Summary
Acts upstream of or within determination of left/right symmetry. Located in centrosome and ciliary basal body. Orthologous to human SSX2IP (SSX family member 2 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See ssx2ipa in Genome Data Viewer
Location:
chromosome: 2
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (1988108..2008457)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (1645302..1665651)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene BCL10 immune signaling adaptor Neighboring gene mucolipin TRP cation channel 3a Neighboring gene tubulin, beta 2A class IIa Neighboring gene solute carrier family 22 member 23

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation. Hori A, et al. EMBO Rep, 2014 Feb. PMID 24397932, Free PMC Article
  2. Conservation of a vitellogenin gene cluster in oviparous vertebrates and identification of its traces in the platypus genome. Babin PJ. Gene, 2008 Apr 30. PMID 18343608
  3. Functional analysis of human hematopoietic stem cell gene expression using zebrafish. Eckfeldt CE, et al. PLoS Biol, 2005 Aug. PMID 16089502, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC73314

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within determination of left/right symmetry IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intraciliary transport involved in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
  
is_active_in centriolar satellite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
afadin- and alpha-actinin-binding protein; synovial sarcoma, X breakpoint 2 interacting protein a
Names
SSC2IP

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200835.2 → NP_957129.2  synovial sarcoma, X breakpoint 2 interacting protein a

    See identical proteins and their annotated locations for NP_957129.2

    Status: PROVISIONAL

    Source sequence(s)
    CU693488
    UniProtKB/TrEMBL
    A0A8M1PFW2, X1WH62
    Related
    ENSDARP00000129572.1, ENSDART00000155956.3
    Conserved Domains (1) summary
    pfam11559
    Location:63 → 210
    ADIP; Afadin- and alpha -actinin-Binding

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    1988108..2008457
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009296556.3 → XP_009294831.1  afadin- and alpha-actinin-binding protein isoform X1

    UniProtKB/TrEMBL
    A0A8M3B5U3
    Conserved Domains (1) summary
    pfam11559
    Location:63 → 210
    ADIP; Afadin- and alpha -actinin-Binding
Nucleotide Protein Strain
Heading Accession and Version

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