pvalb7 parvalbumin 7 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pvalb7provided by ZNC
Official Full Name: parvalbumin 7provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-285
See related: Ensembl:ENSDARG00000034705 AllianceGenome:ZFIN:ZDB-GENE-040718-285
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: pvalb; zgc:92782
Summary: Predicted to enable calcium ion binding activity. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system; midbrain interneuron; musculature system; and somite. Orthologous to human PVALB (parvalbumin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (29168694..29242347, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (29219499..29293152, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This study demonstrated that One singular glomerulus (mdG2) exhibits S100 and parvalbumin-positive fibers, apparently originating from all crypt cells plus some microvillous olfactory sensory neuronss.
Title: Combinatorial analysis of calcium-binding proteins in larval and adult zebrafish primary olfactory system identifies differential olfactory bulb glomerular projection fields.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: parvalbumin-7

Names: parvalbumin alpha; parvalbumin-4a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205574.2 → NP_991137.2 parvalbumin-7

See identical proteins and their annotated locations for NP_991137.2

Status: PROVISIONAL

Source sequence(s)

BC076256

UniProtKB/Swiss-Prot

Q6DGT3, Q804W2

UniProtKB/TrEMBL

Q1LWD7

Related

ENSDARP00000040760.5, ENSDART00000040761.7

Conserved Domains (2) summary

cd00051
Location:44 → 103

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam13499
Location:44 → 107

EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007133.7 Reference GRCz11 Primary Assembly

Range

29168694..29242347 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005161792.2 → XP_005161849.1 parvalbumin-7 isoform X1

See identical proteins and their annotated locations for XP_005161849.1

UniProtKB/Swiss-Prot

Q6DGT3, Q804W2

UniProtKB/TrEMBL

Q1LWD7

Related

ENSDARP00000122628.1, ENSDART00000132702.2

Conserved Domains (2) summary

cd00051
Location:44 → 103

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam13499
Location:44 → 107

EF-hand_7; EF-hand domain pair