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acot16 acyl-CoA thioesterase 16 [ Danio rerio (zebrafish) ]

Gene ID: 402867, updated on 27-Mar-2024

Summary

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Official Symbol
acot16provided by ZNC
Official Full Name
acyl-CoA thioesterase 16provided by ZNC
Primary source
ZFIN:ZDB-GENE-041210-201
See related
Ensembl:ENSDARG00000069292 AllianceGenome:ZFIN:ZDB-GENE-041210-201
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
pte2bl2; DKEYP-89C11.1; si:dkeyp-89c11.1
Summary
Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to act upstream of or within lipid metabolic process. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See acot16 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (25651691..25666563)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (25662503..25677365)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA thioesterase 14 Neighboring gene acyl-CoA thioesterase 15 Neighboring gene acyl-CoA thioesterase 17 Neighboring gene acyl-CoA thioesterase 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Bioinformatic identification of genes encoding C1q-domain-containing proteins in zebrafish. Mei J, et al. J Genet Genomics, 2008 Jan. PMID 18222405
  2. An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 as well as reduced host immune response in angiogenesis and migration. Mohseny AB, et al. J Pathol, 2012 Jun. PMID 22297719
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables fatty acyl-CoA hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables thiolester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within acyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
acyl-CoA thioesterase 16; acyl-coenzyme A thioesterase 4; acyl-coenzyme A thioesterase 5
Names
Col8A1.3
peroxisomal acyl-CoA thioesterase 2b like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386815.1 → NP_001373744.1  acyl-CoA thioesterase 16 precursor

    Status: VALIDATED

    Source sequence(s)
    BX511192
    Conserved Domains (2) summary
    pfam04775
    Location:40 → 167
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    pfam08840
    Location:231 → 443
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    25651691..25666563
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021475271.1 → XP_021330946.1  acyl-coenzyme A thioesterase 4 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q6D0
    Related
    ENSDARP00000091490.3, ENSDART00000100717.5
    Conserved Domains (2) summary
    pfam04775
    Location:51 → 178
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    pfam08840
    Location:242 → 453
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

  2. XM_021475269.1 → XP_021330944.1  acyl-coenzyme A thioesterase 5 isoform X3

    UniProtKB/TrEMBL
    A0A8M9Q141
    Conserved Domains (2) summary
    pfam04775
    Location:51 → 178
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    cl21494
    Location:242 → 376
    Abhydrolase; alpha/beta hydrolases

  3. XM_021475268.1 → XP_021330943.1  acyl-coenzyme A thioesterase 4 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PV48
    Conserved Domains (2) summary
    pfam04775
    Location:3 → 130
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    pfam08840
    Location:194 → 405
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394556.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    133234..151700
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001923499.4 → XP_001923534.4  acyl-coenzyme A thioesterase 4 isoform X1

    UniProtKB/TrEMBL
    A0A8M1QHW7
    Conserved Domains (2) summary
    pfam04775
    Location:51 → 178
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    pfam08840
    Location:242 → 453
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

  2. XM_005164836.4 → XP_005164893.2  acyl-coenzyme A thioesterase 4 isoform X3

    UniProtKB/TrEMBL
    A0A8M2BC14
    Conserved Domains (2) summary
    pfam04775
    Location:51 → 178
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    cl21494
    Location:242 → 376
    Abhydrolase; alpha/beta hydrolases

  3. XM_005164835.3 → XP_005164892.2  acyl-coenzyme A thioesterase 4 isoform X2

    UniProtKB/TrEMBL
    Q1LYJ2
    Conserved Domains (2) summary
    pfam04775
    Location:3 → 130
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    pfam08840
    Location:194 → 405
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal
Nucleotide Protein
Heading Accession and Version

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