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snx16 sorting nexin 16 [ Danio rerio (zebrafish) ]

Gene ID: 402964, updated on 25-Apr-2024

Summary

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Official Symbol
snx16provided by ZNC
Official Full Name
sorting nexin 16provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1832
See related
Ensembl:ENSDARG00000046072 AllianceGenome:ZFIN:ZDB-GENE-040426-1832
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:77396
Summary
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in early endosome to late endosome transport; endosome to lysosome transport; and protein targeting to lysosome. Predicted to be active in early endosome and late endosome. Predicted to be extrinsic component of endosome membrane. Orthologous to human SNX16 (sorting nexin 16). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: suggests misassembly
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See snx16 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (42115501..42121814)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (42193768..42200081)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene serine-aspartate repeat-containing protein F-like Neighboring gene aryl-hydrocarbon receptor repressor a Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class M Neighboring gene NEDD4-like E3 ubiquitin-protein ligase WWP1 Neighboring gene regulator of microtubule dynamics 1 Neighboring gene serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Characterization of genetic loss-of-function of Fus in zebrafish. Lebedeva S, et al. RNA Biol, 2017 Jan 2. PMID 27898262, Free PMC Article
  2. An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish. Xu L, et al. Hepatology, 2012 Jun. PMID 22213104
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC77396

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in early endosome to late endosome transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endosome to lysosome transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein targeting to lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sorting nexin-16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205665.1 → NP_991228.1  sorting nexin-16

    See identical proteins and their annotated locations for NP_991228.1

    Status: PROVISIONAL

    Source sequence(s)
    BC065659
    UniProtKB/TrEMBL
    Q6P0D8
    Related
    ENSDARP00000067733.4, ENSDART00000067734.6
    Conserved Domains (2) summary
    cd07276
    Location:63 → 172
    PX_SNX16; The phosphoinositide binding Phox Homology domain of Sorting Nexin 16
    pfam13863
    Location:181 → 230
    DUF4200; Domain of unknown function (DUF4200)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    42115501..42121814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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