ap1m2 adaptor related protein complex 1 subunit mu 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ap1m2provided by ZNC
Official Full Name: adaptor related protein complex 1 subunit mu 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-20
See related: Ensembl:ENSDARG00000096454 AllianceGenome:ZFIN:ZDB-GENE-041114-20
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Ap1m1; zgc:103537
Summary: Predicted to enable clathrin adaptor activity. Acts upstream of or within animal organ development; digestive tract development; and post-Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus and clathrin-coated vesicle membrane. Predicted to be part of clathrin adaptor complex. Predicted to be active in clathrin-coated vesicle. Is expressed in several structures, including digestive system; eye; heart; intestinal bulb primordium; and pleuroperitoneal region. Orthologous to human AP1M2 (adaptor related protein complex 1 subunit mu 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (112694..121799)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (94586..103748)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G39695 (e-PCR)
- UniSTS:26381

fi81h10.y1 (e-PCR)
- UniSTS:198070

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables clathrin adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within animal organ morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within brain development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within digestive tract development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within kidney development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within post-Golgi vesicle-mediated transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of clathrin adaptor complex	IEA Inferred from Electronic Annotation more info
is_active_in clathrin-coated vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: AP-1 complex subunit mu-2

Names: adaptor-related protein complex 1 mu 1 subunit; adaptor-related protein complex 1, mu 2 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205714.1 → NP_991277.1 AP-1 complex subunit mu-2

See identical proteins and their annotated locations for NP_991277.1

Status: PROVISIONAL

Source sequence(s)

AY394943

UniProtKB/TrEMBL

Q6TLG2

Related

ENSDARP00000037980.7, ENSDART00000034505.9

Conserved Domains (1) summary

cd09259
Location:154 → 421

AP-1_Mu1B_Cterm; C-terminal domain of medium Mu1B subunit in epithelial cell-specific clathrin-associated adaptor protein (AP) complex AP-1

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

112694..121799

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009302064.3 → XP_009300339.1 AP-1 complex subunit mu-2 isoform X1

UniProtKB/TrEMBL

A0A8M3B038, F1R3L9

Conserved Domains (1) summary

cd09259
Location:154 → 421

AP-1_Mu1B_Cterm; C-terminal domain of medium Mu1B subunit in epithelial cell-specific clathrin-associated adaptor protein (AP) complex AP-1