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Ccdc39 Coiled-coil domain containing protein 39 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40595, updated on 10-May-2024

Summary

Official Symbol
Ccdc39provided by FlyBase
Official Full Name
Coiled-coil domain containing protein 39provided by FlyBase
Primary source
FLYBASE:FBgn0037276
Locus tag
Dmel_CG17387
See related
AllianceGenome:FB:FBgn0037276
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17387; Dmel\CG17387
Summary
Predicted to be involved in cilium-dependent cell motility; epithelial cilium movement involved in determination of left/right asymmetry; and inner dynein arm assembly. Predicted to be active in axoneme. Is expressed in adult head; chordotonal neurons; spermatogonium; and spermatozoon. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 14. Orthologous to human CCDC39 (coiled-coil domain containing 39). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Ccdc39 in Genome Data Viewer
Location:
82D5-82D5; 3-47.1 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4781120..4784722, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (606842..610444, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antimeros Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene circadian trip Neighboring gene Hus1-like Neighboring gene GDP-mannose pyrophosphorylase B Neighboring gene Bardet-Biedl syndrome 5

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

mobile_element

  • Loc: c4782166-4782069 mobile_element_type = transposon:INE-1{}5045

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cilium movement IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium movement ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cilium-dependent cell motility IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in epithelial cilium movement involved in determination of left/right asymmetry IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in inner dynein arm assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in inner dynein arm assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in axoneme IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in axoneme IEA
Inferred from Electronic Annotation
more info
 
located_in axoneme ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
Coiled-coil domain containing protein 39
Names
CG17387-PA
Ccdc39-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    4781120..4784722 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141238.2NP_649495.1  Coiled-coil domain containing protein 39 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649495.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DMK5, Q9VN57
    Related
    FBpp0078520
    Conserved Domains (1) summary
    COG1196
    Location:200853
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]