U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tram2 translocation associated membrane protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 406344, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
tram2provided by ZNC
Official Full Name
translocation associated membrane protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2024
See related
Ensembl:ENSDARG00000030092 AllianceGenome:ZFIN:ZDB-GENE-040426-2024
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:55869; zgc:76937; wu:fb20c11; wu:fi23a12; zgc:111902
Summary
Predicted to be involved in protein insertion into ER membrane. Predicted to act upstream of or within SRP-dependent cotranslational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in hatching gland; notochord; polster; and splanchnocranium. Orthologous to human TRAM2 (translocation associated membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See tram2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (48116447..48139941)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (47639142..47662635)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene PR domain containing 1c, with ZNF domain Neighboring gene XK related 5a Neighboring gene EF-hand domain (C-terminal) containing 1 Neighboring gene protein eva-1 homolog A-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC111902

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within SRP-dependent cotranslational protein targeting to membrane, translocation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein insertion into ER membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
translocating chain-associated membrane protein 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213071.1 → NP_998236.1  translocating chain-associated membrane protein 2

    See identical proteins and their annotated locations for NP_998236.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046900
    UniProtKB/TrEMBL
    A0A8M1PNJ3, Q802X7
    Related
    ENSDARP00000043937.6, ENSDART00000043938.9
    Conserved Domains (2) summary
    pfam03798
    Location:113 → 312
    TRAM_LAG1_CLN8; TLC domain
    pfam08390
    Location:49 → 110
    TRAM1; TRAM1-like protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    48116447..48139941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005173812.3 → XP_005173869.1  translocating chain-associated membrane protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BL48
    Conserved Domains (2) summary
    pfam03798
    Location:113 → 312
    TRAM_LAG1_CLN8; TLC domain
    pfam08390
    Location:49 → 110
    TRAM1; TRAM1-like protein
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous