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CG2931 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40673, updated on 10-May-2024

Summary

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Official Symbol
CG2931provided by FlyBase
Primary source
FLYBASE:FBgn0037342
Locus tag
Dmel_CG2931
See related
AllianceGenome:FB:FBgn0037342
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg2931; Dmel\CG2931
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in embryonic/larval midgut; embryonic/larval muscle system; and organism. Orthologous to human RBM42 (RNA binding motif protein 42). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG2931 in Genome Data Viewer
Location:
83B2-83B2; 3-47.5 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5567502..5568615, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1393224..1394337, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ras homolog enriched in brain Neighboring gene Collapsin Response Mediator Protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD. Park J, et al. Nucleic Acids Res, 2021 Nov 8. PMID 34551427, Free PMC Article
  2. Rapid Changes in the Translatome during the Conversion of Growth Cones to Synaptic Terminals. Zhang KX, et al. Cell Rep, 2016 Feb 9. PMID 26832407
  3. Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons. Xie Q, et al. Elife, 2021 Jan 11. PMID 33427646, Free PMC Article
  4. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article
  5. spenito is required for sex determination in Drosophila melanogaster. Yan D, et al. Proc Natl Acad Sci U S A, 2015 Sep 15. PMID 26324914, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome HDA PubMed 
part_of precatalytic spliceosome HDA PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2931-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    5567502..5568615 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141295.4 → NP_649552.1  uncharacterized protein Dmel_CG2931 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649552.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VND7
    Related
    FBpp0078402
    Conserved Domains (2) summary
    COG0724
    Location:194 → 280
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12383
    Location:192 → 274
    RRM_RBM42; RNA recognition motif in RNA-binding protein 42 (RBM42) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VND7 Q9VND7

Gene LinkOut

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