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trp - transient receptor potential

Enables ion channel activity and protein dimerization activity. Involved in several processes, including cellular response to anoxia; detection of visible light; and olfactory learning. Located in rhabdomere microvillus membrane. Part of cation channel complex and inaD signaling complex. Is expressed in several structures, including head and visual system. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41; chronic fatigue syndrome; focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 2; and nephrotic syndrome type 2. Orthologous to several human genes including TRPC4 (transient receptor potential cation channel subfamily C member 4) and TRPC5 (transient receptor potential cation channel subfamily C member 5). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa