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cux1b cut-like homeobox 1b [ Danio rerio (zebrafish) ]

Gene ID: 445120, updated on 27-Mar-2024

Summary

Official Symbol
cux1bprovided by ZNC
Official Full Name
cut-like homeobox 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-260
See related
Ensembl:ENSDARG00000043134 AllianceGenome:ZFIN:ZDB-GENE-040801-260
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cutl1; zgc:86612; id:ibd1033
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of Golgi membrane. Predicted to be active in nucleus. Is expressed in several structures, including adaxial cell; cardiovascular system; immature eye; musculature system; and notochord. Orthologous to human CUX1 (cut like homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See cux1b in Genome Data Viewer
Location:
chromosome: 15
Exon count:
23
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (2520344..2543832)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (2556772..2580260)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene WD repeat domain 53 Neighboring gene SRP receptor subunit beta Neighboring gene SH2B adaptor protein 2 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 30b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within intra-Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
cut-like homeobox 1b
Names
cut-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003514.1NP_001003514.1  cut-like homeobox 1b

    See identical proteins and their annotated locations for NP_001003514.1

    Status: PROVISIONAL

    Source sequence(s)
    BC075748
    UniProtKB/TrEMBL
    Q6DI42
    Related
    ENSDARP00000063328.4, ENSDART00000063329.6
    Conserved Domains (2) summary
    pfam08172
    Location:424638
    CASP_C; CASP C terminal
    cl19219
    Location:117209
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    2520344..2543832
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)