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hmgb2b high mobility group box 2b [ Danio rerio (zebrafish) ]

Gene ID: 447936, updated on 19-May-2024

Summary

Official Symbol
hmgb2bprovided by ZNC
Official Full Name
high mobility group box 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040912-122
See related
Ensembl:ENSDARG00000053990 AllianceGenome:ZFIN:ZDB-GENE-040912-122
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hmgb2; hmgb2l; im:6909096; wu:fa20b02; zgc:101854
Summary
Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including axis; gut; neuromast; ovary; and pectoral fin bud. Orthologous to human HMGB2 (high mobility group box 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See hmgb2b in Genome Data Viewer
Location:
chromosome: 23
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (45025911..45029560)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (45264004..45267653, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene transferrin receptor 2 Neighboring gene CTS telomere maintenance complex component 1 Neighboring gene SH3 domain containing GRB2 like 2b, endophilin A1 Neighboring gene si:ch73-168d20.1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding, bending IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
high mobility group protein B2b
Names
high-mobility group box 2, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004674.1NP_001004674.1  high mobility group protein B2b

    See identical proteins and their annotated locations for NP_001004674.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081415
    UniProtKB/TrEMBL
    B2GRJ5, Q66IB6
    Related
    ENSDARP00000153222.1, ENSDART00000188105.1
    Conserved Domains (2) summary
    pfam00505
    Location:97164
    HMG_box; HMG (high mobility group) box
    pfam09011
    Location:778
    HMG_box_2; HMG-box domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    45025911..45029560
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)