atp6v1c1b ATPase H+ transporting V1 subunit C1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atp6v1c1bprovided by ZNC
Official Full Name: ATPase H+ transporting V1 subunit C1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041010-104
See related: Ensembl:ENSDARG00000035880 AllianceGenome:ZFIN:ZDB-GENE-041010-104
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: atp6v1c1l; zgc:92684; si:zc215i13.2
Summary: Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to act upstream of or within proton transmembrane transport. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Is expressed in head mesenchyme; mucus secreting cell; and nervous system. Orthologous to human ATP6V1C1 (ATPase H+ transporting V1 subunit C1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (32947910..32966762)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (33360790..33379642)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

this is the first report on the role of V-ATPase during adult vertebrate regeneration.
Title: V-ATPase proton pumping activity is required for adult zebrafish appendage regeneration.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables proton transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables proton-transporting ATPase activity, rotational mechanism	IBA Inferred from Biological aspect of Ancestor more info
enables proton-transporting ATPase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of proton-transporting V-type ATPase, V1 domain	IEA Inferred from Electronic Annotation more info
part_of vacuolar proton-transporting V-type ATPase, V1 domain	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: V-type proton ATPase subunit C 1-B

Names: ATPase, H+ transporting, lysosomal, V1 subunit C1b; V-ATPase subunit C 1-B; vacuolar proton pump subunit C 1-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005772.2 → NP_001005772.2 V-type proton ATPase subunit C 1-B

See identical proteins and their annotated locations for NP_001005772.2

Status: PROVISIONAL

Source sequence(s)

AL807244

UniProtKB/Swiss-Prot

Q5XIY6, Q801V4

Related

ENSDARP00000052090.6, ENSDART00000052091.7

Conserved Domains (2) summary

cd14785
Location:56 → 76

V-ATPase_C; 3-helical coiled coil [structural motif]

pfam03223
Location:5 → 369

V-ATPase_C; V-ATPase subunit C