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Ldlrad2 low density lipoprotein receptor class A domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 502992, updated on 5-Mar-2024

Summary

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Official Symbol
Ldlrad2provided by RGD
Official Full Name
low density lipoprotein receptor class A domain containing 2provided by RGD
Primary source
RGD:1564888
See related
Ensembl:ENSRNOG00000033503 AllianceGenome:RGD:1564888
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564888
Summary
Predicted to be integral component of membrane. Orthologous to human LDLRAD2 (low density lipoprotein receptor class A domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 9.7), Heart (RPKM 6.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
5q36
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (155062172..155070752, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (149778795..149788335, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (155914517..155922269, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700013G24 gene like Neighboring gene heparan sulfate proteoglycan 2 Neighboring gene interferon induced transmembrane protein 2, pseudogene 3 Neighboring gene ubiquitin specific peptidase 48

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
low-density lipoprotein receptor class A domain-containing protein 2
Names
low density lipoprotein receptor A domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    155062172..155070752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_578500.8 → XP_578500.2  low-density lipoprotein receptor class A domain-containing protein 2

    See identical proteins and their annotated locations for XP_578500.2

    UniProtKB/TrEMBL
    D4A2E6
    Related
    ENSRNOP00000052800.2
    Conserved Domains (2) summary
    cd00112
    Location:183 → 211
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cl00049
    Location:119 → 174
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Nucleotide Protein Strain
Heading Accession and Version

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