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pgap2 post-GPI attachment to proteins 2 [ Danio rerio (zebrafish) ]

Gene ID: 541417, updated on 11-Apr-2024

Summary

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Official Symbol
pgap2provided by ZNC
Official Full Name
post-GPI attachment to proteins 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050320-119
See related
Ensembl:ENSDARG00000044596 AllianceGenome:ZFIN:ZDB-GENE-050320-119
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
frag1; wu:fc51g11; zgc:101568
Summary
Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human PGAP2 (post-GPI attachment to proteins 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See pgap2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (30970702..30994586, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (30935182..30957909, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene stromal interaction molecule 1b Neighboring gene uncharacterized LOC101886778 Neighboring gene ras homolog family member Gb Neighboring gene nuclear cap binding subunit 3 Neighboring gene RAP1 GTPase activating protein 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in GPI anchor biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
post-GPI attachment to proteins factor 2
Names
FGF receptor-activating protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013544.2 → NP_001013562.1  post-GPI attachment to proteins factor 2

    See identical proteins and their annotated locations for NP_001013562.1

    Status: PROVISIONAL

    Source sequence(s)
    BC090817
    UniProtKB/Swiss-Prot
    Q5BL33
    Related
    ENSDART00000100926.5
    Conserved Domains (1) summary
    pfam10277
    Location:19 → 216
    Frag1; Frag1/DRAM/Sfk1 family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    30970702..30994586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005161301.4 → XP_005161358.1  post-GPI attachment to proteins factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B8B3, G1K2N7
    Related
    ENSDARP00000065502.4, ENSDART00000065503.6
    Conserved Domains (1) summary
    pfam10277
    Location:19 → 241
    Frag1; Frag1/DRAM/Sfk1 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BL33.1 GenPept UniProtKB/Swiss-Prot:Q5BL33

Gene LinkOut

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