myd88 myeloid differentiation primary response 88 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: myd88provided by Xenbase
Official Full Name: myeloid differentiation primary response 88provided by Xenbase
Primary source: Xenbase:XB-GENE-486650
See related: Ensembl:ENSXETG00000018434
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: XMyD88; myd88d; myd88-a; myd88-b
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	6	NC_030682.2 (7349723..7362273, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	Unplaced Scaffold	NW_016683377.1 (1269077..1274618)

Chromosome 6 - NC_030682.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables TIR domain binding	IEA Inferred from Electronic Annotation more info
enables Toll-like receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within MyD88-dependent toll-like receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in Toll signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in defense response to Gram-positive bacterium	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within inflammatory response	IEA Inferred from Electronic Annotation more info
involved_in innate immune response	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within innate immune response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info
involved_in toll-like receptor 4 signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: myeloid differentiation primary response protein MyD88

Names: myeloid differentiation primary response gene (88)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001016837.2 → NP_001016837.1 myeloid differentiation primary response protein MyD88

See identical proteins and their annotated locations for NP_001016837.1

Status: PROVISIONAL

Source sequence(s)

CR855486

UniProtKB/Swiss-Prot

Q28DJ2

UniProtKB/TrEMBL

A0A1B8YA45, A0A8F2WAP5, F6VWP1

Related

ENSXETP00000039929.3, ENSXETT00000039929.4

Conserved Domains (2) summary

smart00255
Location:148 → 282

TIR; Toll - interleukin 1 - resistance

cd08312
Location:24 → 102

Death_MyD88; Death domain of Myeloid Differentation primary response protein MyD88