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igf2bp3 insulin like growth factor 2 mRNA binding protein 3 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 549893, updated on 5-Mar-2024

Summary

Official Symbol
igf2bp3provided by Xenbase
Official Full Name
insulin like growth factor 2 mRNA binding protein 3provided by Xenbase
Primary source
Xenbase:XB-GENE-483018
See related
Ensembl:ENSXETG00000007396
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
B3; IMP; imp3; koc1; vera; imp-3; vg1rbp; vickz3; Vg1-RBP; igf2bp3-a; igf2bp3-b
Orthologs
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Genomic context

Location:
chromosome: 6
Exon count:
17
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (40262085..40327974, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (34732940..34796135)

Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene glycoprotein nmb Neighboring gene mitochondrial assembly of ribosomal large subunit 1 Neighboring gene uncharacterized LOC100498040 Neighboring gene transformer 2 alpha homolog

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within germ cell development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within germ cell migration IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mRNA transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within sex determination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
insulin-like growth factor 2 mRNA-binding protein 3
Names
Vg1 RBP

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017139.2NP_001017139.1  insulin-like growth factor 2 mRNA-binding protein 3

    See identical proteins and their annotated locations for NP_001017139.1

    Status: PROVISIONAL

    Source sequence(s)
    CR761008
    UniProtKB/TrEMBL
    A0A8J0PJ32, B0JZ55
    Conserved Domains (3) summary
    cd00105
    Location:289354
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd12627
    Location:177
    RRM1_IGF2BP3; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    cd12630
    Location:81156
    RRM2_IGF2BP3; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    40262085..40327974 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031903400.1XP_031759260.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X1

    UniProtKB/TrEMBL
    B0JZ55, F6SCY4
    Related
    ENSXETP00000016106.5, ENSXETT00000016106.5
    Conserved Domains (4) summary
    cd12630
    Location:44119
    RRM2_IGF2BP3; RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    cd22490
    Location:170245
    KH-I_IGF2BP1_rpt1; first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins
    cl00098
    Location:248342
    KH-I; K homology (KH) RNA-binding domain, type I
    cl17169
    Location:940
    RRM_SF; RNA recognition motif (RRM) superfamily
  2. XM_031903401.1XP_031759261.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8J1JRQ1
    Conserved Domains (1) summary
    cl00098
    Location:128222
    KH-I; K homology (KH) RNA-binding domain, type I