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rrbp1a ribosome binding protein 1a [ Danio rerio (zebrafish) ]

Gene ID: 553448, updated on 25-Apr-2024

Summary

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Official Symbol
rrbp1aprovided by ZNC
Official Full Name
ribosome binding protein 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9795
See related
Ensembl:ENSDARG00000013763 AllianceGenome:ZFIN:ZDB-GENE-030131-9795
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb360; sb:cb360; wu:fa66b07; wu:fb58g03; zgc:171356; si:dkey-76k16.7
Summary
Predicted to act upstream of or within protein transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including anterior axial hypoblast; axial mesoderm; axis; cardiovascular system; and hatching gland. Orthologous to human RRBP1 (ribosome binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See rrbp1a in Genome Data Viewer
Location:
chromosome: 13
Exon count:
29
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (33611707..33639050, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (33502162..33529505, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene jagged canonical Notch ligand 2a Neighboring gene cofilin 1 (non-muscle), like Neighboring gene si:dkey-76k16.6 Neighboring gene sorting nexin 5 Neighboring gene mitochondrial genome maintenance exonuclease 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity. Ma X, et al. Sci Adv, 2020 Jan. PMID 32064346, Free PMC Article
  2. Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish. Kossack ME, et al. Genetics, 2019 Jan. PMID 30446521, Free PMC Article
  3. Investigation of the effects of estrogen on skeletal gene expression during zebrafish larval head development. Pashay Ahi E, et al. PeerJ, 2016. PMID 27069811, Free PMC Article
  4. Unifying developmental programs for embryonic and postembryonic neurogenesis in the zebrafish retina. Xu B, et al. Development, 2020 Jun 19. PMID 32467236
  5. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC171356

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosome binding protein 1; ribosome-binding protein 1a
Names
ribosome binding protein 1 homolog a (dog)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145555.1 → NP_001139027.1  ribosome-binding protein 1a

    Status: PROVISIONAL

    Source sequence(s)
    BX005372
    UniProtKB/TrEMBL
    A0A8M1NQ07, B8A4D7
    Related
    ENSDARP00000118039.1, ENSDART00000133073.2
    Conserved Domains (5) summary
    pfam04554
    Location:179 → 220
    Extensin_2; Extensin-like region
    pfam05104
    Location:33 → 210
    Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
    pfam13851
    Location:708 → 885
    GAS; Growth-arrest specific micro-tubule binding
    pfam15035
    Location:1049 → 1186
    Rootletin; Ciliary rootlet component, centrosome cohesion
    cl19252
    Location:623 → 683
    MreC; rod shape-determining protein MreC

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    33611707..33639050 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005156964.4 → XP_005157021.1  ribosome binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B316
    Conserved Domains (5) summary
    pfam04554
    Location:179 → 220
    Extensin_2; Extensin-like region
    pfam05104
    Location:33 → 210
    Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
    pfam13851
    Location:708 → 885
    GAS; Growth-arrest specific micro-tubule binding
    pfam15035
    Location:1049 → 1186
    Rootletin; Ciliary rootlet component, centrosome cohesion
    cl19252
    Location:623 → 683
    MreC; rod shape-determining protein MreC

  2. XM_005156963.4 → XP_005157020.1  ribosome binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B3S2
    Conserved Domains (5) summary
    pfam04554
    Location:179 → 220
    Extensin_2; Extensin-like region
    pfam05104
    Location:33 → 210
    Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
    pfam13851
    Location:708 → 882
    GAS; Growth-arrest specific micro-tubule binding
    pfam15035
    Location:1046 → 1183
    Rootletin; Ciliary rootlet component, centrosome cohesion
    cl19252
    Location:623 → 683
    MreC; rod shape-determining protein MreC

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001123059.1: Suppressed sequence

    Description
    NM_001123059.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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