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cldn23.1 claudin 23.1 [ Danio rerio (zebrafish) ]

Gene ID: 553515, updated on 27-Mar-2024

Summary

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Official Symbol
cldn23.1provided by ZNC
Official Full Name
claudin 23.1provided by ZNC
Primary source
ZFIN:ZDB-GENE-091204-28
See related
Ensembl:ENSDARG00000028096 AllianceGenome:ZFIN:ZDB-GENE-091204-28
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cldn23a; cldn23a2; si:ch211-95j8.2
Summary
Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in cell junction and membrane. Predicted to be integral component of membrane. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN23 (claudin 23). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See cldn23.1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
1
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (15046837..15048824, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (15088718..15090709, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene si:dkey-88l16.5 Neighboring gene uncharacterized LOC100537265 Neighboring gene claudin 23.2 Neighboring gene prostate androgen-regulated mucin-like protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Meta-Analysis of Grainyhead-Like Dependent Transcriptional Networks: A Roadmap for Identifying Novel Conserved Genetic Pathways. Mathiyalagan N, et al. Genes (Basel), 2019 Oct 31. PMID 31683705, Free PMC Article
  2. Phylogenetic revision of the claudin gene family. Baltzegar DA, et al. Mar Genomics, 2013 Sep. PMID 23726886
  3. What makes a bad egg? Egg transcriptome reveals dysregulation of translational machinery and novel fertility genes important for fertilization. Cheung CT, et al. BMC Genomics, 2019 Jul 15. PMID 31307377, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
  
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
claudin 23a; claudin-23
Names
claudin 23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386714.1 → NP_001373643.1  claudin 23a precursor

    Status: VALIDATED

    Source sequence(s)
    CR536613, CT027832
    UniProtKB/TrEMBL
    A0A8M1Q785, F1Q6Q0
    Conserved Domains (1) summary
    cl21598
    Location:5 → 179
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    15046837..15048824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001337411.5 → XP_001337447.2  claudin-23

    UniProtKB/TrEMBL
    F1Q6Q0
    Related
    ENSDARP00000030329.4, ENSDART00000038401.5
    Conserved Domains (1) summary
    cl21598
    Location:5 → 179
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
Nucleotide Protein
Heading Accession and Version

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