cyp1c1 cytochrome P450, family 1, subfamily C, polypeptide 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cyp1c1provided by ZNC
Official Full Name: cytochrome P450, family 1, subfamily C, polypeptide 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-501
See related: Ensembl:ENSDARG00000101195 AllianceGenome:ZFIN:ZDB-GENE-050522-501
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:110607
Summary: Enables coumarin 7-hydroxylase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; and testosterone 6-beta-hydroxylase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: Un

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	Unplaced Scaffold	NW_003336436.1 (103570..106641)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_003336436.1 (103570..106641)

NW_003336436.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

a potential role of CYP1C1 and CYP1C2 in the local circulation failure induced by AHR2 activation in the dorsal midbrain of the zebrafish embryo.
Title: Role of zebrafish cytochrome P450 CYP1C genes in the reduced mesencephalic vein blood flow caused by activation of AHR2.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables aromatase activity	IEA Inferred from Electronic Annotation more info
enables benzo(a)pyrene 7,8-dioxygenase activity	IDA Inferred from Direct Assay more info	PubMed
enables benzo(a)pyrene 9,10-dioxygenase activity	IDA Inferred from Direct Assay more info	PubMed
enables coumarin 7-hydroxylase activity	IDA Inferred from Direct Assay more info	PubMed
enables heme binding	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables monooxygenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info
enables testosterone 6-beta-hydroxylase activity	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome P450 1C1

NP_001018446.2

EC 1.14.14.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.