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dhx57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [ Danio rerio (zebrafish) ]

Gene ID: 555250, updated on 27-Mar-2024

Summary

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Official Symbol
dhx57provided by ZNC
Official Full Name
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4078
See related
Ensembl:ENSDARG00000057660 AllianceGenome:ZFIN:ZDB-GENE-030131-4078
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc68d07; wu:fc68d07; si:ch211-250c4.7
Summary
Predicted to enable RNA binding activity. Orthologous to human DHX57 (DExH-box helicase 57). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See dhx57 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
23
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (8320455..8353485, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (7988647..8021484, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain 110 molecular ruler complex subunit Neighboring gene atlastin GTPase 2 Neighboring gene galactose mutarotase Neighboring gene endothelial PAS domain protein 1b Neighboring gene protein kinase C, epsilon b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Pla2g6 Deficiency in Zebrafish Leads to Dopaminergic Cell Death, Axonal Degeneration, Increased β-Synuclein Expression, and Defects in Brain Functions and Pathways. Sánchez E, et al. Mol Neurobiol, 2018 Aug. PMID 29344929
  2. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative ATP-dependent RNA helicase DHX57
XP_001921063.3
XP_021328300.1
XP_021328305.1
XP_021336395.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    8320455..8353485 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021480720.1 → XP_021336395.1  putative ATP-dependent RNA helicase DHX57 isoform X1

    UniProtKB/TrEMBL
    A0A8M9QNL6, F1QCB1
    Related
    ENSDARP00000074801.4, ENSDART00000080351.6
    Conserved Domains (3) summary
    COG1643
    Location:537 → 1419
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    COG5175
    Location:309 → 510
    MOT2; Transcriptional repressor [Transcription]
    cl21463
    Location:198 → 239
    UBA_like_SF; UBA domain-like superfamily

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394863.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    348753..362497 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472625.1 → XP_021328300.1  putative ATP-dependent RNA helicase DHX57 isoform X3

    UniProtKB/TrEMBL
    A0A8M9Q4T8
    Conserved Domains (1) summary
    COG1643
    Location:10 → 504
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394864.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    351..14131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472630.1 → XP_021328305.1  putative ATP-dependent RNA helicase DHX57 isoform X2

    UniProtKB/TrEMBL
    A0A8M9Q4U2
    Conserved Domains (3) summary
    COG1643
    Location:537 → 801
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    COG5175
    Location:309 → 510
    MOT2; Transcriptional repressor [Transcription]
    cl21463
    Location:198 → 239
    UBA_like_SF; UBA domain-like superfamily

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395305.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    164865..197959 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001921028.5 → XP_001921063.3  putative ATP-dependent RNA helicase DHX57 isoform X1

    UniProtKB/TrEMBL
    A0A2R8Q3V8, A0A8M1QHI5
    Conserved Domains (3) summary
    COG1643
    Location:538 → 1420
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    COG5175
    Location:310 → 511
    MOT2; Transcriptional repressor [Transcription]
    cl21463
    Location:199 → 240
    UBA_like_SF; UBA domain-like superfamily
Nucleotide Protein Strain
Heading Accession and Version

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