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ccdc22 coiled-coil domain containing 22 [ Danio rerio (zebrafish) ]

Gene ID: 556259, updated on 27-Mar-2024

Summary

Official Symbol
ccdc22provided by ZNC
Official Full Name
coiled-coil domain containing 22provided by ZNC
Primary source
ZFIN:ZDB-GENE-050913-93
See related
Ensembl:ENSDARG00000052379 AllianceGenome:ZFIN:ZDB-GENE-050913-93
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:114058
Summary
Predicted to enable cullin family protein binding activity. Predicted to be involved in positive regulation of ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within protein transport. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome 2. Orthologous to human CCDC22 (coiled-coil domain containing 22). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 8
Exon count:
16
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (23615149..23638012)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (23593910..23616773)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene WASP actin nucleation promoting factor b Neighboring gene solute carrier family 38 member 5b Neighboring gene 5'-nucleotidase domain containing 2 Neighboring gene transfer RNA histidin (anticodon GUG)

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC114058

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cullin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in positive regulation of ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in centrosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025485.1NP_001020656.1  coiled-coil domain-containing protein 22

    See identical proteins and their annotated locations for NP_001020656.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097121
    UniProtKB/Swiss-Prot
    Q4V909
    Related
    ENSDARP00000090542.4, ENSDART00000099769.6
    Conserved Domains (1) summary
    pfam05667
    Location:1602
    DUF812; Protein of unknown function (DUF812)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    23615149..23638012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)