macc1 MET transcriptional regulator MACC1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: macc1provided by ZNC
Official Full Name: MET transcriptional regulator MACC1provided by ZNC
Primary source: ZFIN:ZDB-GENE-091006-3
See related: Ensembl:ENSDARG00000040717 AllianceGenome:ZFIN:ZDB-GENE-091006-3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Acts upstream of or within embryonic cranial skeleton morphogenesis. Predicted to be active in cytoplasm. Is expressed in eye; midbrain hindbrain boundary; otic vesicle; stomodeum; and telencephalon. Orthologous to human MACC1 (MET transcriptional regulator MACC1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (19637445..19644458)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (19831626..19838639)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryonic cranial skeleton morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: metastasis-associated in colon cancer protein 1

Names: metastasis associated in colon cancer 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199766.1 → NP_001186695.1 metastasis-associated in colon cancer protein 1

Status: VALIDATED

Source sequence(s)

BX005389

UniProtKB/TrEMBL

A0A8M1NXI5, E7FG38

Related

ENSDARP00000114832.1, ENSDART00000135359.2

Conserved Domains (4) summary

cd01670
Location:747 → 822

Death; Death Domain: a protein-protein interaction domain

cl02517
Location:220 → 261

ZU5; ZU5 domain

cl14633
Location:660 → 741

DD; Death Domain Superfamily of protein-protein interaction domains

cl17036
Location:557 → 621

SH3; Src Homology 3 domain superfamily