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ces2b carboxylesterase 2b [ Danio rerio (zebrafish) ]

Gene ID: 561967, updated on 27-Mar-2024

Summary

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Official Symbol
ces2bprovided by ZNC
Official Full Name
carboxylesterase 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041014-96
See related
AllianceGenome:ZFIN:ZDB-GENE-041014-96
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb62a02; si:ch211-93f2.1
Summary
Predicted to enable carboxylic ester hydrolase activity; mannosyl-oligosaccharide mannosidase activity; and phospholipase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in gut; intestinal bulb; and liver. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See ces2b in Genome Data Viewer
Location:
chromosome: 25
Exon count:
37
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (30362898..30429684, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (29919796..29986629, complement)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene TopBP1-interacting, checkpoint, and replication regulator Neighboring gene protein disulfide isomerase family A, member 3 Neighboring gene transfer RNA arginine (anticodon ACG) Neighboring gene transfer RNA arginine (anticodon ACG)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Molecular cloning and characterization of an atypical butyrylcholinesterase-like protein in zebrafish. Tan KS, et al. Comp Biochem Physiol B Biochem Mol Biol, 2021 Aug-Sep. PMID 33662568
  2. Defining hepatic dysfunction parameters in two models of fatty liver disease in zebrafish larvae. Howarth DL, et al. Zebrafish, 2013 Jun. PMID 23697887, Free PMC Article
  3. Crosstalk of oxidative damage, apoptosis, and autophagy under endoplasmic reticulum (ER) stress involved in thifluzamide-induced liver damage in zebrafish (Danio rerio). Yang Y, et al. Environ Pollut, 2018 Dec. PMID 30408879
  4. Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation. Passeri MJ, et al. Hepatology, 2009 Feb. PMID 19127516, Free PMC Article
  5. Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish. Cinaroglu A, et al. Hepatology, 2011 Aug. PMID 21538441, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cholinesterase activity IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
carboxylesterase 2b; uncharacterized protein si:ch211-93f2.1
Names
novel carboxylesterase domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    30362898..30429684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021470705.1 → XP_021326380.1  uncharacterized protein si:ch211-93f2.1

    UniProtKB/TrEMBL
    A0A8M9PZ17
    Conserved Domains (1) summary
    pfam00135
    Location:27 → 539
    COesterase; Carboxylesterase family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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