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si:dkey-46g23.5 si:dkey-46g23.5 [ Danio rerio (zebrafish) ]

Gene ID: 562067, updated on 27-Mar-2024

Summary

Official Symbol
si:dkey-46g23.5provided by ZNC
Official Full Name
si:dkey-46g23.5provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9306
See related
Ensembl:ENSDARG00000008835 AllianceGenome:ZFIN:ZDB-GENE-030131-9306
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa56g11; wu:fa56g11
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See si:dkey-46g23.5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
34
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (3432960..3448095, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (3650707..3665842, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene zgc:171446 Neighboring gene zgc:171445 Neighboring gene zgc:165453 Neighboring gene zgc:171426

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein LOC562067
Names
alpha-2-macroglobulin-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001201405.2NP_001188334.2  uncharacterized protein LOC562067 precursor

    Status: VALIDATED

    Source sequence(s)
    BC152015, BX322654, CABZ01040995, CD594314
    UniProtKB/TrEMBL
    A0A8M1NYK0, F1QS86
    Related
    ENSDARP00000073345.6, ENSDART00000078886.6
    Conserved Domains (6) summary
    cd02897
    Location:9941269
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:776864
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:170261
    A2M_N; MG2 domain
    pfam07677
    Location:13881477
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:10461269
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:506650
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    3432960..3448095 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)