megf6 multiple EGF like domains 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: megf6provided by ZNC
Official Full Name: multiple EGF like domains 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-070112-1202
See related: AllianceGenome:ZFIN:ZDB-GENE-070112-1202
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:158328
Summary: Predicted to enable calcium ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 15

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (35253371..35345485)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (35395402..35487516)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A role for the MEGF6 gene in predisposition to osteoporosis.
Title: A role for the MEGF6 gene in predisposition to osteoporosis.

Submit: New GeneRIF Correction

General gene information

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Markers

fb94c04.x1 (e-PCR)
- UniSTS:203552

z3760 (e-PCR), detects polymorphism
- UniSTS:205205

z40609 (e-PCR), detects polymorphism
- UniSTS:238546

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

General protein information

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Preferred Names: uncharacterized protein LOC567225

Names: EGF-like-domain, multiple 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080189.1 → NP_001073658.1 uncharacterized protein LOC567225

See identical proteins and their annotated locations for NP_001073658.1

Status: PREDICTED

Source sequence(s)

BC129204

UniProtKB/TrEMBL

A1L1T4

Conserved Domains (3) summary

pfam07546
Location:15 → 83

EMI; EMI domain

pfam14670
Location:345 → 380

FXa_inhibition; Coagulation Factor Xa inhibitory site

cl00057
Location:159 → 209

vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...