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zyg11l zyg-11 family member, cell cycle regulator, like [ Danio rerio (zebrafish) ]

Gene ID: 567429, updated on 27-Mar-2024

Summary

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Official Symbol
zyg11lprovided by ZNC
Official Full Name
zyg-11 family member, cell cycle regulator, likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5941
See related
Ensembl:ENSDARG00000101799 AllianceGenome:ZFIN:ZDB-GENE-030131-5941
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fi26e04; wu:fi26e04; si:ch1073-82l19.1
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. Orthologous to human ZYG11A (zyg-11 family member A, cell cycle regulator) and ZYG11B (zyg-11 family member B, cell cycle regulator). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See zyg11l in Genome Data Viewer
Location:
chromosome: 2
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (2927463..2957459, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (3085574..3115567, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B, subunit 5 epsilon Neighboring gene leucine-rich repeat-containing protein 38-like Neighboring gene phosphoinositide-3-kinase, regulatory subunit 3a (gamma) Neighboring gene intracisternal A particle-promoted polypeptide

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS. Tingaud-Sequeira A, et al. Mol Genet Genomic Med, 2020 Oct. PMID 32738032, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of Cul2-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein zyg-11 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    2927463..2957459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009296723.2 → XP_009294998.1  protein zyg-11 homolog isoform X3

    UniProtKB/TrEMBL
    A0A8M3AY84
    Conserved Domains (4) summary
    COG4886
    Location:98 → 269
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd00020
    Location:476 → 578
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00116
    Location:70 → 257
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:70 → 98
    LRR_AMN1; leucine-rich repeat [structural motif]

  2. XM_009296721.2 → XP_009294996.1  protein zyg-11 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8M3ANH3
    Conserved Domains (4) summary
    COG4886
    Location:98 → 269
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd00020
    Location:504 → 606
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00116
    Location:70 → 257
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:70 → 98
    LRR_AMN1; leucine-rich repeat [structural motif]

  3. XM_690724.8 → XP_695816.5  protein zyg-11 homolog isoform X1

    UniProtKB/TrEMBL
    A0A0R4IGL5, A0A8N7TEE8
    Related
    ENSDARP00000134209.1, ENSDART00000162505.2
    Conserved Domains (4) summary
    COG4886
    Location:98 → 269
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd00020
    Location:505 → 607
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00116
    Location:70 → 257
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:70 → 98
    LRR_AMN1; leucine-rich repeat [structural motif]
Nucleotide Protein Strain
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