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pleca - plectin a

Predicted to enable ankyrin binding activity and structural molecule activity. Predicted to be a structural constituent of cytoskeleton and structural constituent of muscle. Acts upstream of or within locomotory behavior and skeletal muscle tissue development. Predicted to be located in cytoskeleton. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including focal adhesion; hemidesmosome; and sarcolemma. Predicted to colocalize with intermediate filament. Is expressed in epidermis and yolk syncytial layer. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2Q; epidermolysis bullosa simplex; epidermolysis bullosa simplex Ogna type; and epidermolysis bullosa simplex with muscular dystrophy. Orthologous to human PLEC (plectin). [provided by Alliance of Genome Resources, Apr 2022]

Genes similar to pleca

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Species Gene Architecture aa