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si:ch211-241e1.3 si:ch211-241e1.3 [ Danio rerio (zebrafish) ]

Gene ID: 567640, updated on 11-Apr-2024

Summary

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Official Symbol
si:ch211-241e1.3provided by ZNC
Official Full Name
si:ch211-241e1.3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-230
See related
Ensembl:ENSDARG00000022615 AllianceGenome:ZFIN:ZDB-GENE-030131-230
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb17h02; wu:fb17h02
Summary
Predicted to enable signaling receptor binding activity. Predicted to be involved in animal organ morphogenesis; neuron projection development; and tissue development. Predicted to act upstream of or within several processes, including cell adhesion; regulation of cell migration; and regulation of embryonic development. Predicted to be active in basement membrane. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See si:ch211-241e1.3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
31
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (944341..985487, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (1073933..1115057, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene si:ch211-241e1.5 Neighboring gene gastrula zinc finger protein XlCGF49.1-like Neighboring gene calcium channel, voltage-dependent, R type, alpha 1E subunit b Neighboring gene RNA polymerase II subunit D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. Nagendran M, et al. Development, 2015 Jan 15. PMID 25519245, Free PMC Article
  2. Screen for genes differentially expressed during regeneration of the zebrafish caudal fin. Padhi BK, et al. Dev Dyn, 2004 Nov. PMID 15376328
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables extracellular matrix structural constituent IBA
Inferred from Biological aspect of Ancestor
more info
  
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in animal organ morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of cell migration IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
  
involved_in tissue development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in basement membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
laminin subunit alpha-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    944341..985487 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_690939.8 → XP_696031.6  laminin subunit alpha-3

    UniProtKB/TrEMBL
    A0A8N7TFA0
    Related
    ENSDARP00000119869.1, ENSDART00000140540.3
    Conserved Domains (8) summary
    smart00282
    Location:873 → 1011
    LamG; Laminin G domain
    cd00055
    Location:125 → 162
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:1215 → 1340
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00053
    Location:196 → 226
    Laminin_EGF; Laminin EGF domain
    pfam06009
    Location:733 → 850
    Laminin_II; Laminin Domain II
    pfam06008
    Location:293 → 541
    Laminin_I; Laminin Domain I
    cl22855
    Location:142 → 263
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
    cl27218
    Location:520 → 599
    OmpH; Outer membrane protein (OmpH-like)
Nucleotide Protein Strain
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