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larp1b La ribonucleoprotein 1B [ Danio rerio (zebrafish) ]

Gene ID: 568156, updated on 11-Apr-2024

Summary

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Official Symbol
larp1bprovided by ZNC
Official Full Name
La ribonucleoprotein 1Bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4154
See related
Ensembl:ENSDARG00000061169 AllianceGenome:ZFIN:ZDB-GENE-030131-4154
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc76b04; wu:fc76b04
Summary
Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of translation. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human LARP1B (La ribonucleoprotein 1B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See larp1b in Genome Data Viewer
Location:
chromosome: 17
Exon count:
19
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (26753972..26802816)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (26735123..26784378)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene calmodulin 1a Neighboring gene NRDE-2, necessary for RNA interference, domain containing Neighboring gene progesterone receptor membrane component 2 Neighboring gene acetylserotonin O-methyltransferase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Antisense RNAs during early vertebrate development are divided in groups with distinct features. Pillay S, et al. Genome Res, 2021 Jun. PMID 33795334, Free PMC Article
  2. Single Cell Transcriptome Sequencing of Zebrafish Testis Revealed Novel Spermatogenesis Marker Genes and Stronger Leydig-Germ Cell Paracrine Interactions. Qian P, et al. Front Genet, 2022. PMID 35360857, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA cap binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA stabilization IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
la-related protein 1; la-related protein 1B
Names
La ribonucleoprotein domain family, member 1B
la related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    26753972..26802816
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158557.4 → XP_005158614.1  la-related protein 1B isoform X1

    UniProtKB/TrEMBL
    A0A8M2B4Y8
    Conserved Domains (2) summary
    smart00684
    Location:884 → 922
    DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
    cd08034
    Location:325 → 397
    LARP_1_2; La RNA-binding domain proteins similar to La-related proteins 1 and 2

  2. XM_009293108.3 → XP_009291383.1  la-related protein 1B isoform X2

    UniProtKB/TrEMBL
    A0A8M3B2G7
    Conserved Domains (2) summary
    smart00684
    Location:883 → 921
    DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
    cd08034
    Location:324 → 396
    LARP_1_2; La RNA-binding domain proteins similar to La-related proteins 1 and 2

  3. XM_691468.8 → XP_696560.3  la-related protein 1B isoform X3

    UniProtKB/TrEMBL
    A0A8N7T839, F1Q931
    Related
    ENSDARP00000007794.7, ENSDART00000025096.10
    Conserved Domains (2) summary
    smart00684
    Location:849 → 887
    DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
    cd08034
    Location:325 → 397
    LARP_1_2; La RNA-binding domain proteins similar to La-related proteins 1 and 2

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394994.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    14..39464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473187.1 → XP_021328862.1  la-related protein 1B isoform X4

    UniProtKB/TrEMBL
    A0A8M9PCV0
    Conserved Domains (3) summary
    smart00684
    Location:581 → 619
    DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
    cl02755
    Location:22 → 94
    LAM; LA motif RNA-binding domain
    cl27057
    Location:684 → 808
    ADK; Adenylate kinase

  2. XM_021473188.1 → XP_021328863.1  la-related protein 1B isoform X4

    UniProtKB/TrEMBL
    A0A8M9PCV0
    Conserved Domains (3) summary
    smart00684
    Location:581 → 619
    DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
    cl02755
    Location:22 → 94
    LAM; LA motif RNA-binding domain
    cl27057
    Location:684 → 808
    ADK; Adenylate kinase

  3. XM_021473189.1 → XP_021328864.1  la-related protein 1B isoform X5

    UniProtKB/TrEMBL
    A0A8M9PVK3
    Conserved Domains (3) summary
    smart00684
    Location:546 → 584
    DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function
    cl02755
    Location:22 → 94
    LAM; LA motif RNA-binding domain
    cl27057
    Location:649 → 773
    ADK; Adenylate kinase
Nucleotide Protein Strain
Heading Accession and Version

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