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cog4 component of oligomeric golgi complex 4 [ Danio rerio (zebrafish) ]

Gene ID: 569049, updated on 11-Apr-2024

Summary

Official Symbol
cog4provided by ZNC
Official Full Name
component of oligomeric golgi complex 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-060312-33
See related
Ensembl:ENSDARG00000054264 AllianceGenome:ZFIN:ZDB-GENE-060312-33
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:136860
Summary
Acts upstream of or within proteoglycan metabolic process and skeletal system development. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of Golgi transport complex. Is expressed in nervous system; otic epithelium; otic vesicle protrusion; and pharyngeal arch cartilage. Used to study Saul-Wilson syndrome. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Orthologous to human COG4 (component of oligomeric golgi complex 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See cog4 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
19
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (29024286..29039270)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (28753136..28768120)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene docking protein 4 Neighboring gene dynein axonemal assembly factor 1 Neighboring gene neuritin 1-like b Neighboring gene THAP domain containing 11 Neighboring gene glucose-fructose oxidoreductase domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC136860

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within proteoglycan metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within skeletal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
part_of Golgi transport complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
conserved oligomeric Golgi complex subunit 4
Names
COG complex subunit 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039823.1NP_001034912.1  conserved oligomeric Golgi complex subunit 4

    See identical proteins and their annotated locations for NP_001034912.1

    Status: PROVISIONAL

    Source sequence(s)
    BC114292
    UniProtKB/Swiss-Prot
    Q29RB1
    Related
    ENSDARP00000070899.2, ENSDART00000076425.5
    Conserved Domains (1) summary
    pfam08318
    Location:180489
    COG4; COG4 transport protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    29024286..29039270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)