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oxr1b oxidation resistance 1b [ Danio rerio (zebrafish) ]

Gene ID: 570476, updated on 7-Apr-2024

Summary

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Official Symbol
oxr1bprovided by ZNC
Official Full Name
oxidation resistance 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2438
See related
Ensembl:ENSDARG00000063310 AllianceGenome:ZFIN:ZDB-GENE-030131-2438
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc07g10; wu:fc07g10; si:dkeyp-84f11.5
Summary
Predicted to be involved in response to oxidative stress. Predicted to be active in nucleus. Is expressed in central nervous system; head; lateral line ganglion; and olfactory pit. Human ortholog(s) of this gene implicated in cerebellar hyplasia/atrophy, epilepsy, and global developmental delay. Orthologous to human OXR1 (oxidation resistance 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See oxr1b in Genome Data Viewer
Location:
chromosome: 19
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (7309050..7406922, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (7390125..7487982, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108180139 Neighboring gene squalene epoxidase b Neighboring gene NAD(P)HX epimerase Neighboring gene RAB25, member RAS oncogene family a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The embryonic expression patterns of zebrafish genes encoding LysM-domains. Laroche FJ, et al. Gene Expr Patterns, 2013 Oct. PMID 23567754
  2. Expression profiling and functional characterization of the duplicated Oxr1b gene in zebrafish. Xu H, et al. Comp Biochem Physiol Part D Genomics Proteomics, 2021 Sep. PMID 34111665
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
oxidation resistance protein 1; oxidation resistance protein 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045203.1 → NP_001038668.1  oxidation resistance protein 1b

    See identical proteins and their annotated locations for NP_001038668.1

    Status: PROVISIONAL

    Source sequence(s)
    BX890617
    UniProtKB/TrEMBL
    A0A8N7XJA0, F1Q4W8, Q1LVA3
    Related
    ENSDARP00000086811.5, ENSDART00000092379.6
    Conserved Domains (3) summary
    smart00584
    Location:585 → 749
    TLDc; domain in TBC and LysM domain containing proteins
    COG1388
    Location:3 → 45
    LysM; LysM repeat [Cell wall/membrane/envelope biogenesis]
    pfam01476
    Location:3 → 45
    LysM; LysM domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    7309050..7406922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159459.3 → XP_005159516.1  oxidation resistance protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B610
    Conserved Domains (3) summary
    smart00584
    Location:654 → 814
    TLDc; domain in TBC and LysM domain containing proteins
    COG1388
    Location:73 → 141
    LysM; LysM repeat [Cell wall/membrane/envelope biogenesis]
    pfam01476
    Location:99 → 141
    LysM; LysM domain

  2. XM_005159458.3 → XP_005159515.1  oxidation resistance protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B612, I3ISS4
    Related
    ENSDARP00000125967.1, ENSDART00000151137.3
    Conserved Domains (3) summary
    smart00584
    Location:681 → 841
    TLDc; domain in TBC and LysM domain containing proteins
    COG1388
    Location:73 → 141
    LysM; LysM repeat [Cell wall/membrane/envelope biogenesis]
    pfam01476
    Location:99 → 141
    LysM; LysM domain

  3. XM_009294057.3 → XP_009292332.1  oxidation resistance protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M3AK20
    Related
    ENSDARP00000086807.5, ENSDART00000092375.6
    Conserved Domains (1) summary
    smart00584
    Location:80 → 240
    TLDc; domain in TBC and LysM domain containing proteins
Nucleotide Protein Strain
Heading Accession and Version

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