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cept1b choline/ethanolamine phosphotransferase 1b [ Danio rerio (zebrafish) ]

Gene ID: 570720, updated on 15-May-2024

Summary

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Official Symbol
cept1bprovided by ZNC
Official Full Name
choline/ethanolamine phosphotransferase 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-071004-33
See related
Ensembl:ENSDARG00000021177 AllianceGenome:ZFIN:ZDB-GENE-071004-33
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cept1; zgc:171762; CH1073-272H17.1
Summary
Predicted to enable diacylglycerol cholinephosphotransferase activity and ethanolaminephosphotransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum membrane. Orthologous to human CEPT1 (choline/ethanolamine phosphotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See cept1b in Genome Data Viewer
Location:
chromosome: 22
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (869600..881937, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (852702..865253, complement)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene cryptochrome circadian regulator 4 Neighboring gene DENN/MADD domain containing 2Db Neighboring gene DNA-damage regulated autophagy modulator 2b Neighboring gene serine/threonine kinase 38b Neighboring gene potassium channel tetramerization domain containing 20

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Canonical Wnt Signaling Remodels Lipid Metabolism in Zebrafish Hepatocytes following Ras Oncogenic Insult. Yao Y, et al. Cancer Res, 2018 Oct 1. PMID 30065049
  2. Pth4, an ancient parathyroid hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway. Suarez-Bregua P, et al. FASEB J, 2017 Feb. PMID 28148780, Free PMC Article
  3. Eumetazoan cryptochrome phylogeny and evolution. Haug MF, et al. Genome Biol Evol, 2015 Jan 18. PMID 25601102, Free PMC Article
  4. Composition and evolution of the vertebrate and mammalian selenoproteomes. Mariotti M, et al. PLoS One, 2012. PMID 22479358, Free PMC Article
  5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables 1-alkenyl-2-acylglycerol choline phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables diacylglycerol cholinephosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables diacylglycerol cholinephosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ethanolaminephosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ethanolaminephosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphotransferase activity, for other substituted phosphate groups IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphatidylethanolamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
choline/ethanolaminephosphotransferase 1
Names
choline/ethanolamine phosphotransferase 1
NP_001103187.1
XP_009294039.1
XP_021325046.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109717.1 → NP_001103187.1  choline/ethanolaminephosphotransferase 1

    See identical proteins and their annotated locations for NP_001103187.1

    Status: PROVISIONAL

    Source sequence(s)
    BC151968
    UniProtKB/TrEMBL
    A0A8M1NES9, A7MBY6
    Related
    ENSDARP00000036669.5, ENSDART00000035514.7
    Conserved Domains (1) summary
    cl00453
    Location:43 → 381
    CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    869600..881937 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021469371.1 → XP_021325046.1  choline/ethanolaminephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PRW3
    Conserved Domains (1) summary
    cl00453
    Location:43 → 381
    CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase

  2. XM_009295764.3 → XP_009294039.1  choline/ethanolaminephosphotransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M3B557
    Conserved Domains (1) summary
    cl00453
    Location:43 → 211
    CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
Nucleotide Protein Strain
Heading Accession and Version

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