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Vsig2 V-set and immunoglobulin domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 57276, updated on 5-Mar-2024

Summary

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Official Symbol
Vsig2provided by MGI
Official Full Name
V-set and immunoglobulin domain containing 2provided by MGI
Primary source
MGI:MGI:1928009
See related
Ensembl:ENSMUSG00000001943 AllianceGenome:MGI:1928009
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CTX; Ctm; 1190004B15Rik; 2210413P10Rik
Summary
Predicted to be integral component of plasma membrane. Orthologous to human VSIG2 (V-set and immunoglobulin domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 244.5), bladder adult (RPKM 48.8) and 3 other tissues See more
Orthologs
human all
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Genomic context

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Location:
9 A4; 9 20.78 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (37450551..37455501)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (37539255..37544205)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23809 Neighboring gene Myb/SANT-like DNA-binding domain containing 2 Neighboring gene endothelial cell-specific adhesion molecule Neighboring gene STARR-seq mESC enhancer starr_23812 Neighboring gene neurogranin Neighboring gene predicted gene, 46107

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates. Chrétien I, et al. Eur J Immunol, 1998 Dec. PMID 9862345
  2. Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Gu Z, et al. PLoS One, 2015. PMID 25826454, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC117653

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 

General protein information

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Preferred Names
V-set and immunoglobulin domain-containing protein 2
Names
CT-like protein
CTM
cortical thymocyte receptor (X. laevis CTX) like
cortical thymocyte-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020518.2 → NP_065264.2  V-set and immunoglobulin domain-containing protein 2 precursor

    See identical proteins and their annotated locations for NP_065264.2

    Status: VALIDATED

    Source sequence(s)
    AC105958, AK008920, AV018710, BB869209
    Consensus CDS
    CCDS22980.1
    UniProtKB/Swiss-Prot
    Q9CVA4, Q9D0T4, Q9Z109
    Related
    ENSMUSP00000002008.6, ENSMUST00000002008.7
    Conserved Domains (3) summary
    smart00410
    Location:152 → 235
    IG_like; Immunoglobulin like
    pfam07686
    Location:32 → 143
    V-set; Immunoglobulin V-set domain
    cl11960
    Location:153 → 231
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    37450551..37455501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Z109.2 GenPept UniProtKB/Swiss-Prot:Q9Z109

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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