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gpr173 G protein-coupled receptor 173 [ Danio rerio (zebrafish) ]

Gene ID: 57926, updated on 27-Mar-2024

Summary

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Official Symbol
gpr173provided by ZNC
Official Full Name
G protein-coupled receptor 173provided by ZNC
Primary source
ZFIN:ZDB-GENE-000710-1
See related
Ensembl:ENSDARG00000042922 AllianceGenome:ZFIN:ZDB-GENE-000710-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sreb3; zgc:194661; zgc:194688
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including digestive system; heart; integument; nervous system; and pleuroperitoneal region. Orthologous to human GPR173 (G protein-coupled receptor 173). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See gpr173 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (23410925..23426640, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (23391299..23405390, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene si:dkey-16n15.6 Neighboring gene SUV39H1 histone lysine methyltransferase a Neighboring gene forkhead box P3b Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system. Matsumoto M, et al. Biochem Biophys Res Commun, 2000 Jun 7. PMID 10833454
  2. Phoenixin-20 suppresses food intake, modulates glucoregulatory enzymes, and enhances glycolysis in zebrafish. Rajeswari JJ, et al. Am J Physiol Regul Integr Comp Physiol, 2020 May 1. PMID 32208925, Free PMC Article
  3. Phoenixin-20 Stimulates mRNAs Encoding Hypothalamo-Pituitary-Gonadal Hormones, is Pro-Vitellogenic, and Promotes Oocyte Maturation in Zebrafish. Rajeswari JJ, et al. Sci Rep, 2020 Apr 14. PMID 32286445, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable G-protein coupled receptor 173
Names
super conserved receptor expressed in brain 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131498.1 → NP_571573.1  probable G-protein coupled receptor 173

    See identical proteins and their annotated locations for NP_571573.1

    Status: PROVISIONAL

    Source sequence(s)
    AB040806
    UniProtKB/Swiss-Prot
    Q9I918
    UniProtKB/TrEMBL
    B0S582
    Related
    ENSDARP00000063004.2, ENSDART00000063005.3
    Conserved Domains (1) summary
    cd15217
    Location:37 → 365
    7tmA_SREB3_GPR173; super conserved receptor expressed in brain 3 (or GPR173), member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    23410925..23426640 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167058.4 → XP_005167115.1  probable G-protein coupled receptor 173 isoform X1

    See identical proteins and their annotated locations for XP_005167115.1

    UniProtKB/Swiss-Prot
    Q9I918
    UniProtKB/TrEMBL
    B0S582
    Conserved Domains (1) summary
    cd15217
    Location:37 → 365
    7tmA_SREB3_GPR173; super conserved receptor expressed in brain 3 (or GPR173), member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I918.1 GenPept UniProtKB/Swiss-Prot:Q9I918

Gene LinkOut

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