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Islr immunoglobulin superfamily containing leucine-rich repeat [ Rattus norvegicus (Norway rat) ]

Gene ID: 686539, updated on 5-Mar-2024

Summary

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Official Symbol
Islrprovided by RGD
Official Full Name
immunoglobulin superfamily containing leucine-rich repeatprovided by RGD
Primary source
RGD:1596359
See related
Ensembl:ENSRNOG00000048924 AllianceGenome:RGD:1596359
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human ISLR (immunoglobulin superfamily containing leucine rich repeat). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 170.9), Uterus (RPKM 165.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Islr in Genome Data Viewer
Location:
8q24
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (67467013..67469989, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (58571155..58574128, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (62946732..62949675, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 33 Neighboring gene uncharacterized LOC120094173 Neighboring gene signaling receptor and transporter of retinol STRA6 Neighboring gene uncharacterized LOC134480059 Neighboring gene immunoglobulin superfamily containing leucine-rich repeat 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Abonnenc M, et al. Circ Res, 2013 Oct 25. PMID 24006456
  2. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Principe S, et al. Proteomics, 2013 May. PMID 23533145, Free PMC Article
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
immunoglobulin superfamily containing leucine-rich repeat protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126300.1 → NP_001119772.1  immunoglobulin superfamily containing leucine-rich repeat protein precursor

    See identical proteins and their annotated locations for NP_001119772.1

    Status: PROVISIONAL

    Source sequence(s)
    BC160841
    UniProtKB/TrEMBL
    A0A8I6AEA4, A6J4Z4, B1H232
    Related
    ENSRNOP00000090688.1, ENSRNOT00000106345.1
    Conserved Domains (5) summary
    TIGR00864
    Location:153 → 227
    PCC; polycystin cation channel protein
    sd00033
    Location:32 → 51
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 158
    LRR_8; Leucine rich repeat
    cd00096
    Location:265 → 287
    Ig; Ig strand C [structural motif]
    cl11960
    Location:239 → 343
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    67467013..67469989 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006243176.5 → XP_006243238.1  immunoglobulin superfamily containing leucine-rich repeat protein isoform X1

    See identical proteins and their annotated locations for XP_006243238.1

    UniProtKB/TrEMBL
    A0A8I6AEA4, A6J4Z4, B1H232
    Related
    ENSRNOP00000067644.1
    Conserved Domains (5) summary
    TIGR00864
    Location:153 → 227
    PCC; polycystin cation channel protein
    sd00033
    Location:32 → 51
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 158
    LRR_8; Leucine rich repeat
    cd00096
    Location:265 → 287
    Ig; Ig strand C [structural motif]
    cl11960
    Location:239 → 343
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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