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TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 702208, updated on 11-Apr-2024

Summary

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Official Symbol
TIE1provided by VGNC
Official Full Name
tyrosine kinase with immunoglobulin like and EGF like domains 1provided by VGNC
Primary source
VGNC:VGNC:78355
Locus tag
EGK_00658
See related
Ensembl:ENSMMUG00000010660
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See TIE1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (181138608..181161635, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (42794970..42818118)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114672740 Neighboring gene ELOVL fatty acid elongase 1 Neighboring gene uncharacterized LOC106998150 Neighboring gene cell division cycle 20 Neighboring gene chromosome 1 C1orf210 homolog Neighboring gene uncharacterized LOC114672736

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase receptor Tie-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    181138608..181161635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015137399.2 → XP_014992885.1  tyrosine-protein kinase receptor Tie-1

    UniProtKB/TrEMBL
    A0A1D5QER9, A0A663DGD0, A0A8J8XCU7, F7B4Q3, G7MGE5
    Related
    ENSMMUP00000013971.3, ENSMMUT00000014912.4
    Conserved Domains (7) summary
    smart00219
    Location:839 → 1107
    TyrKc; Tyrosine kinase, catalytic domain
    cd00054
    Location:227 → 256
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00063
    Location:644 → 736
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05089
    Location:836 → 1132
    PTKc_Tie1; Catalytic domain of the Protein Tyrosine Kinase, Tie1
    pfam00041
    Location:548 → 632
    fn3; Fibronectin type III domain
    pfam00047
    Location:129 → 210
    ig; Immunoglobulin domain
    pfam07974
    Location:315 → 344
    EGF_2; EGF-like domain
Nucleotide Protein
Heading Accession and Version

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