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irgf4 immunity-related GTPase family, f4 [ Danio rerio (zebrafish) ]

Gene ID: 767672, updated on 19-Jun-2024

Summary

Official Symbol
irgf4provided by ZNC
Official Full Name
immunity-related GTPase family, f4provided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-404
See related
AllianceGenome:ZFIN:ZDB-GENE-060929-404
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:152960
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See irgf4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (938322..944042)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (1169685..1175322)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene GTPase IMAP family member 8-like Neighboring gene CD209 antigen-like protein E Neighboring gene C-type lectin domain family 7 member A-like Neighboring gene uncharacterized LOC100535033

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General protein information

Preferred Names
immunity-related GTPase family, f4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    938322..944042
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171533.4XP_005171590.1  immunity-related GTPase family, f4

    UniProtKB/TrEMBL
    A0A8M2BIV5
    Conserved Domains (4) summary
    cd00021
    Location:90127
    BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
    cd00162
    Location:1960
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam13863
    Location:145246
    DUF4200; Domain of unknown function (DUF4200)
    cl21455
    Location:291502
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001076611.1: Suppressed sequence

    Description
    NM_001076611.1: This RefSeq was removed because currently there is insufficient support for the transcript.