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stk17al serine/threonine kinase 17a like [ Danio rerio (zebrafish) ]

Gene ID: 777621, updated on 27-Mar-2024

Summary

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Official Symbol
stk17alprovided by ZNC
Official Full Name
serine/threonine kinase 17a likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061103-427
See related
Ensembl:ENSDARG00000015922 AllianceGenome:ZFIN:ZDB-GENE-061103-427
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fi11h05; fi32b12; wu:fi11h05; wu:fi32b12; zgc:153952
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and positive regulation of apoptotic process. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in nucleus. Orthologous to human STK17B (serine/threonine kinase 17b). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 3
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (16841939..16872909)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (16692154..16723109)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene si:dkey-30j10.5 Neighboring gene leucine rich repeat containing 3Cb Neighboring gene ATPase H+ transporting V0 subunit a1a Neighboring gene caveolae associated protein 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. IRF4 drives clonal evolution and lineage choice in a zebrafish model of T-cell lymphoma. Amanda S, et al. Nat Commun, 2022 May 3. PMID 35504924, Free PMC Article
  2. Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. Takeuchi M, et al. J Comp Neurol, 2017 May 1. PMID 27615194
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
serine/threonine kinase 17a like; serine/threonine-protein kinase 17A
NP_001071197.1
XP_017210081.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077729.1 → NP_001071197.1  serine/threonine kinase 17a like

    See identical proteins and their annotated locations for NP_001071197.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125921
    UniProtKB/TrEMBL
    A0A8M1NC43, A0JML4
    Related
    ENSDARP00000010065.8, ENSDART00000023985.10
    Conserved Domains (2) summary
    smart00220
    Location:27 → 285
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:16 → 285
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    16841939..16872909
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017354592.2 → XP_017210081.1  serine/threonine-protein kinase 17A isoform X1

    UniProtKB/TrEMBL
    A0A8M1NC43, A0JML4
    Conserved Domains (2) summary
    smart00220
    Location:27 → 285
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:16 → 285
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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