mindy3 MINDY lysine 48 deubiquitinase 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mindy3provided by ZNC
Official Full Name: MINDY lysine 48 deubiquitinase 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-061110-13
See related: Ensembl:ENSDARG00000028715 AllianceGenome:ZFIN:ZDB-GENE-061110-13
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fam188a; fb94a02; wu:fb94a02; wu:fy30f06; zgc:153892
Summary: Predicted to enable Lys48-specific deubiquitinase activity. Predicted to act upstream of or within apoptotic process and protein K48-linked deubiquitination. Predicted to be located in nucleus. Orthologous to human MINDY3 (MINDY lysine 48 deubiquitinase 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (28270103..28371330)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (28335480..28436707)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb94a02.x1 (e-PCR)
- UniSTS:203546

fc62a05 (e-PCR)
- UniSTS:189475

Z3633 (e-PCR)
- UniSTS:47917

G47644 (e-PCR)
- UniSTS:108418

NoName (e-PCR)
- UniSTS:238330

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables K48-linked deubiquitinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables K48-linked deubiquitinase activity	IEA Inferred from Electronic Annotation more info
enables cysteine-type deubiquitinase activity	IEA Inferred from Electronic Annotation more info
enables cysteine-type peptidase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within apoptotic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ubiquitin carboxyl-terminal hydrolase MINDY-3

Names: deubiquitinating enzyme MINDY-3; family with sequence similarity 188, member A; protein FAM188A; ubiquitin carboxyl-terminal hydrolase FAM188A

NP_001071224.1

EC 3.4.19.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.