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myo15b myosin XVB [ Danio rerio (zebrafish) ]

Gene ID: 795537, updated on 27-Mar-2024

Summary

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Official Symbol
myo15bprovided by ZNC
Official Full Name
myosin XVBprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4797
See related
Ensembl:ENSDARG00000074852 AllianceGenome:ZFIN:ZDB-GENE-030131-4797
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fd60h05; si:dkeyp-67e6.5
Summary
Located in cytoplasm and nucleus. Orthologous to human MYO15B (myosin XVB). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See myo15b in Genome Data Viewer
Location:
chromosome: 12
Exon count:
49
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (33661649..33714846, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (33560666..33608405, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene tudor and KH domain containing Neighboring gene transmembrane protein 94 Neighboring gene E3 ubiquitin-protein ligase RBBP6-like Neighboring gene LLGL scribble cell polarity complex component 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Choksi SP, et al. Development, 2014 Sep. PMID 25139857, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in system development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
myosin XVB

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    33661649..33714846 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017358549.2 → XP_017214038.2  myosin XVB

    UniProtKB/TrEMBL
    A0A8M6Z8Z4
    Related
    ENSDARP00000127409.1, ENSDART00000153135.3
    Conserved Domains (8) summary
    cd13201
    Location:1787 → 1887
    FERM_C_MyoXV; FERM domain C-lobe of Myosin XV (MyoXV/Myo15)
    pfam00612
    Location:221 → 241
    IQ; IQ calmodulin-binding motif
    pfam00784
    Location:1476 → 1581
    MyTH4; MyTH4 domain
    cl02480
    Location:359 → 503
    MyTH4; MyTH4 domain
    cl09511
    Location:1590 → 1791
    FERM_B-lobe; FERM domain B-lobe
    cl17036
    Location:1262 → 1316
    SH3; Src Homology 3 domain superfamily
    cl22853
    Location:5 → 182
    Motor_domain; Myosin and Kinesin motor domain
    cl25800
    Location:812 → 962
    GGN; Gametogenetin

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394855.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    252915..305917 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472579.1 → XP_021328254.1  myosin XVB

    UniProtKB/TrEMBL
    A0A8M9PTM5
    Conserved Domains (8) summary
    cd13201
    Location:1787 → 1887
    FERM_C_MyoXV; FERM domain C-lobe of Myosin XV (MyoXV/Myo15)
    pfam00612
    Location:221 → 241
    IQ; IQ calmodulin-binding motif
    pfam00784
    Location:1476 → 1581
    MyTH4; MyTH4 domain
    cl02480
    Location:359 → 503
    MyTH4; MyTH4 domain
    cl09511
    Location:1590 → 1791
    FERM_B-lobe; FERM domain B-lobe
    cl17036
    Location:1262 → 1316
    SH3; Src Homology 3 domain superfamily
    cl22853
    Location:5 → 182
    Motor_domain; Myosin and Kinesin motor domain
    cl26464
    Location:818 → 955
    Atrophin-1; Atrophin-1 family
Nucleotide Protein Strain
Heading Accession and Version

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