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rin3 Ras and Rab interactor 3 [ Danio rerio (zebrafish) ]

Gene ID: 799244, updated on 27-Mar-2024

Summary

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Official Symbol
rin3provided by ZNC
Official Full Name
Ras and Rab interactor 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8871
See related
Ensembl:ENSDARG00000077618 AllianceGenome:ZFIN:ZDB-GENE-030131-8871
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fk30a05; wu:fk30a05; si:dkey-246c17.2
Summary
Predicted to enable GTPase activator activity. Predicted to act upstream of or within signal transduction. Orthologous to human RIN3 (Ras and Rab interactor 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See rin3 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (33453577..33484913)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (33501166..33532402)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 28A Neighboring gene synaptosome associated protein 23.1 Neighboring gene synaptosome associated protein 23.2 Neighboring gene transmembrane protein 121Aa Neighboring gene parathyroid hormone 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
enables small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ras and Rab interactor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    33453577..33484913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001339586.8 → XP_001339622.2  ras and Rab interactor 3

    UniProtKB/TrEMBL
    A0A8M1PZC2, E7FC22
    Related
    ENSDARP00000127920.1, ENSDART00000156894.2
    Conserved Domains (3) summary
    cd10395
    Location:149 → 249
    SH2_RIN3; Src homology 2 (SH2) domain found in Ras and Rab interactor 3 (RIN3)-like proteins
    pfam02204
    Location:803 → 905
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
    cl00155
    Location:942 → 1024
    UBQ; Ubiquitin-like proteins
Nucleotide Protein Strain
Heading Accession and Version

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